{"id":18000,"date":"2023-11-20T14:50:40Z","date_gmt":"2023-11-20T13:50:40Z","guid":{"rendered":"https:\/\/www.omni-biotic.com\/cs-cz\/?p=18000"},"modified":"2024-03-19T14:12:41Z","modified_gmt":"2024-03-19T13:12:41Z","slug":"probioticke-bakterie-pri-hojeni-ran","status":"publish","type":"post","link":"https:\/\/www.omni-biotic.com\/cs-cz\/blog\/probioticke-bakterie-pri-hojeni-ran\/","title":{"rendered":"Mohou probiotick\u00e9 bakterie pomoci p\u0159i hojen\u00ed ran?"},"content":{"rendered":"\t\t
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Pro\u010d se n\u011bkter\u00e9 r\u00e1ny nehoj\u00ed?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Kolik o\u0161et\u0159ujete p\u0159ibli\u017en\u011b ro\u010dn\u011b pacient\u016f s chronick\u00fdmi ranami a kter\u00e9 bakterie jsou nej\u010dast\u011bj\u0161\u00edmi p\u0159\u00ed\u010dinami nehoj\u00edc\u00edch se ran?<\/em><\/p>

To je obt\u00ed\u017en\u00e9 odhadnout, proto\u017ee pacienti s ranami v jsou o\u0161et\u0159ov\u00e1ni v r\u016fzn\u00fdch odv\u011btv\u00edch. Pokud jde o poopera\u010dn\u00ed infekce, jsou to samoz\u0159ejm\u011b p\u0159edev\u0161\u00edm p\u0159\u00edslu\u0161n\u00ed chirurgov\u00e9, kte\u0159\u00ed poskytuj\u00ed l\u00e9\u010dbu, d\u00e1le c\u00e9vn\u00ed specialist\u00e9, dermatologov\u00e9, v\u0161eobecn\u00ed chirurgov\u00e9 a diabetologov\u00e9. Chronick\u00e9 r\u00e1ny<\/strong> tedy nejsou p\u0159i\u0159azeny k ur\u010dit\u00e9 specializaci. Z rozs\u00e1hl\u00e9 studie PMV z roku 2016 v\u0161ak v\u00edme, \u017ee v t\u00e9 dob\u011b se jednalo o p\u0159ibli\u017en\u011b t\u0159i miliony pacient\u016f s chronick\u00fdmi ranami.\u00a0 Co se t\u00fd\u010de p\u0159\u00ed\u010din infekc\u00ed ran, n\u00e1rodn\u00ed i mezin\u00e1rodn\u00ed studie identifikovaly bakterii Staphylococcus aureus <\/strong><\/em>ve v\u00edce ne\u017e 50 % p\u0159\u00edpad\u016f, z nich\u017e p\u0159ibli\u017en\u011b 9 % tvo\u0159il Staphylococcus aureus <\/em>rezistentn\u00ed v\u016f\u010di meticilinu (MRSA). Zde je v\u0161ak t\u0159eba zd\u016fraznit, \u017ee dokud MRSA z\u016fst\u00e1v\u00e1 v r\u00e1n\u011b, je tato bakterie stejn\u011b citliv\u00e1 na na\u0161e antiseptika jako „norm\u00e1ln\u00ed“ Staphylococcus aureus.<\/strong> Skute\u010dn\u00fdm probl\u00e9mem se pak st\u00e1v\u00e1, kdy\u017e se povrchov\u00e1 infekce r\u00e1ny rozvine v hlubokou infekci a roz\u0161\u00ed\u0159\u00ed se do cel\u00e9ho t\u011bla. V\u00fdb\u011br antibiotik,<\/strong> kter\u00e1 je pak zapot\u0159eb\u00ed nasadit, je pak kv\u016fli rezistenci t\u00e9to bakterie pom\u011brn\u011b omezen\u00fd. Dal\u0161\u00ed bakteri\u00ed, kter\u00e1 \u010dasto kolonizuje chronick\u00e9 r\u00e1ny, je Pseudomonas aeruginosa<\/em><\/strong> (30 %), a stejn\u011b tak i enterobakterie.<\/strong> V\u0161echny tyto druhy bakteri\u00ed jsou hlavn\u00edmi nep\u0159\u00e1teli funk\u010dn\u00edho hojen\u00ed ran.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Diabetes a obt\u00ed\u017en\u00e9 hojen\u00ed ran<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Jsou p\u0159\u00ed\u010dinou \u0161patn\u011b se hoj\u00edc\u00edch ran v\u017edy z\u00e1va\u017en\u00e1 poran\u011bn\u00ed, nebo mohou k tomuto probl\u00e9mu v\u00e9st i mal\u00e1 \u0161kr\u00e1bnut\u00ed? A pro\u010d jsou poruchami hojen\u00ed ran tak \u010dasto posti\u017eeni diabetici?<\/em><\/p>

Tato r\u00e1ny se neobjevuj\u00ed jen tak z ni\u010deho nic. U star\u0161\u00edch pacient\u016f s poruchami krevn\u00edho ob\u011bhu<\/strong> jsou r\u00e1ny na nohou \u010dasto zp\u016fsobeny drobn\u00fdmi poran\u011bn\u00edmi. Drobn\u00e9 nara\u017eeniny<\/strong> p\u0159i pr\u00e1ci na zahrad\u011b, \u0161kr\u00e1bnut\u00ed o trny r\u016f\u017e\u00ed nebo \u0161t\u00edpnut\u00ed hmyzem. U diabetik\u016f<\/strong> jsou to \u010dasto otev\u0159en\u00e9 prole\u017eeniny na nohou.<\/strong> Proto\u017ee se u mnoha diabetik\u016f vyvine takzvan\u00e1 polyneuropatie,<\/strong> co\u017e znamen\u00e1, \u017ee nervy ji\u017e nevys\u00edlaj\u00ed p\u0159\u00edslu\u0161n\u00e9 sign\u00e1ly bolesti p\u0159i tlaku, tvo\u0159\u00ed se u diabetick\u00fdch pacient\u016f \u010dast\u011bji puch\u00fd\u0159e,<\/strong> zejm\u00e9na na plosce nohy nebo na vy\u010dn\u00edvaj\u00edc\u00edch kostech. Tyto se pak snadn\u011bji otev\u0159ou a zm\u011bn\u00ed se v chronick\u00e9 r\u00e1ny.<\/strong><\/p><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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V\u00fdvoj v oblasti hojen\u00ed ran<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Laik by mohl m\u00edt n\u011bkdy ten dojem, \u017ee se v oblasti p\u00e9\u010de o r\u00e1ny ned\u011bje tolik jako v jin\u00fdch l\u00e9ka\u0159sk\u00fdch oborech. Je to pravda, nebo jak\u00e1 je zde v\u011bdeck\u00e1 realita?<\/em><\/p>

Ano i ne. V posledn\u00edch letech, kdy se v\u0161e a v\u0161ichni soust\u0159edili na COVID-19,<\/strong> jsme se nedo\u010dkali \u017e\u00e1dn\u00fdch skute\u010dn\u00fdch inovac\u00ed v l\u00e9\u010db\u011b ran, a\u010dkoli jsme zaznamenali, \u017ee se v tomto obdob\u00ed pacineti s poran\u011bn\u00edmi \u010dasto b\u00e1li nav\u0161t\u00edvit nemocnice a ambulance ze strachu z naka\u017een\u00ed nebo nedostatku odborn\u00e9ho person\u00e1lu,<\/strong> v d\u016fsledku \u010deho\u017e jsme byli sv\u011bdky velmi v\u00e1\u017en\u00fdch a hlubok\u00fdch ran. Modern\u00ed terapie ran je na sv\u011bt\u011b ji\u017e 40 let a miln\u00edkem v hojen\u00ed ran bylo zaveden\u00ed tzv. „vlhk\u00e9 terapie ran“.<\/strong> D\u0159\u00edve se m\u011blo za to, \u017ee r\u00e1ny mus\u00ed „vyschnout“. To sice st\u00e1le plat\u00ed pro akutn\u00ed r\u00e1ny, ale zaveden\u00ed vlhk\u00e9 terapie bylo po\u017eehn\u00e1n\u00edm pro chronick\u00e9 r\u00e1ny. I kdy\u017e v posledn\u00ed dob\u011b nedo\u0161lo v t\u00e9to oblasti k \u017e\u00e1dn\u00fdm dal\u0161\u00edm skute\u010dn\u00fdm pokrok\u016fm, materi\u00e1ly k hojen\u00ed ran jsou st\u00e1le lep\u0161\u00ed a \u00fa\u010din\u011bj\u0161\u00ed,<\/strong> m\u00e9n\u011b lep\u00ed a jsou ten\u010d\u00ed. Za zm\u00ednku stoj\u00ed tak\u00e9 rozvoj podtlakov\u00e9 terapie,<\/strong> p\u0159i n\u00ed\u017e se r\u00e1na p\u0159ekryje podlo\u017ekou houbovit\u00e9ho charakteru a f\u00f3li\u00ed, \u010d\u00edm\u017e se zde udr\u017euje vlhkost a \u010distota p\u016fsoben\u00edm podtlaku, co\u017e stimuluje hojen\u00ed r\u00e1ny. Zdravotnick\u00fd pr\u016fmysl n\u00e1m nav\u00edc v sou\u010dasn\u00e9 dob\u011b poskytuje \u0161irokou \u0161k\u00e1lu \u00fa\u010dinn\u00fdch antimikrobi\u00e1ln\u00edch l\u00e1tek<\/strong> a roztok\u016f, kter\u00e9 n\u00e1m pom\u00e1haj\u00ed kontrolovat infek\u010dnost r\u00e1ny<\/strong> zven\u010d\u00ed. Nemysl\u00edm si v\u0161ak, \u017ee m\u016f\u017eeme v posledn\u00edch 15 letech hovo\u0159it raketov\u00e9 v\u011bd\u011b nebo obrovsk\u00fdch miln\u00edc\u00edch.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Antibiotika a poruchy hojen\u00ed ran<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Antibiotika byla velk\u00fdm po\u017eehn\u00e1n\u00edm pro lidstvo, ale rostouc\u00ed rezistence v\u016f\u010di t\u011bmto l\u00e9k\u016fm se st\u00e1v\u00e1 st\u00e1le v\u011bt\u0161\u00edm probl\u00e9mem. Nalezneme zde probl\u00e9m i v souvislosti s p\u00e9\u010d\u00ed o r\u00e1ny?<\/em><\/p>

Ka\u017ed\u00e1 chronick\u00e1 r\u00e1na je kolonizov\u00e1na \u0161irokou \u0161k\u00e1lou bakteri\u00e1ln\u00edch kmen\u016f. Pokud je analyzujeme pomoc\u00ed PCR diagnostiky, nalezneme zde\u00a0 a\u017e 70 r\u016fzn\u00fdch druh\u016f bakteri\u00ed.<\/strong> Ale ne proti v\u0161em mus\u00edme nutn\u011b nasadit antibiotika.<\/strong> Je-li prok\u00e1z\u00e1na p\u0159\u00edtomnost bakteri\u00ed, mus\u00edme si vz\u00edt pod lupu stav r\u00e1ny i pacienta. Ka\u017ed\u00fd l\u00e9ka\u0159 by m\u011bl nejprve zjistit, zda je r\u00e1na pouze kolonizovan\u00e1 bakteriemi<\/strong> a pacientovi zde nehroz\u00ed \u017e\u00e1dn\u00e9 nebezpe\u010d\u00ed,<\/strong> nebo zda se jedn\u00e1 o lok\u00e1ln\u00ed \u010di dokonce syst\u00e9movou infekci.<\/strong> U pacient\u016f s chronick\u00fdmi ranami se toti\u017e opakovan\u011b objevuj\u00ed n\u00e1b\u011bhy na infekce a zde by bez rozmyslu bylo poka\u017ed\u00e9 p\u0159edeps\u00e1no antibiotikum. To by typick\u00e9ho pacienta s obt\u00ed\u017en\u00fdm hojen\u00edm ran postihlo dvakr\u00e1t a\u017e t\u0159ikr\u00e1t ro\u010dn\u011b. Zde je pak v\u00fdvoj rezistence<\/strong> p\u0159edem naprogramov\u00e1n.<\/strong><\/p>

Antibiotika<\/strong> jsou samoz\u0159ejm\u011b skute\u010dn\u011b mocnou zbran\u00ed proti infekc\u00edm, ale u pacient\u016f s chronick\u00fdmi ranami by m\u011bla b\u00fdt v\u017edy u\u017e\u00edv\u00e1na s opatrnost\u00ed. Proto je zde vhodn\u00e9 hledat alternativy, proto\u017ee po\u010det rezistentn\u00edch bakteri\u00ed<\/strong> se p\u0159es ve\u0161kerou na\u0161i opatrnost st\u00e1le zvy\u0161uje.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Riziko zan\u00edcen\u00ed ran v nemocni\u010dn\u00edch za\u0159\u00edzen\u00edch<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Jak vysok\u00e9 je riziko infekc\u00ed ran v nemocnici? Existuj\u00ed ur\u010dit\u00e9 skupiny pacient\u016f, kter\u00e9 jsou obzvl\u00e1\u0161t\u011b ohro\u017eeny?<\/em><\/p>

Star\u0161\u00ed lid\u00e9 – tak\u00e9 proto, \u017ee s p\u0159ib\u00fdvaj\u00edc\u00edm v\u011bkem se metabolick\u00e9 procesy v t\u011ble zpomaluj\u00ed.<\/strong> Ale p\u0159ev\u00e1\u017ene jsou to pacienti trp\u00edc\u00ed\u00a0 cukrovkou nebo obezitou,<\/strong> stejn\u011b jako pacienti, kte\u0159\u00ed trp\u00ed oboj\u00edm, a to hlavn\u011b d\u00edky tzv. metabolick\u00e9mu syndromu.<\/strong> Tito pacienti trp\u00ed komplexn\u00ed poruchou metabolismu, kter\u00e1 zt\u011b\u017euje hojen\u00ed ran. Krom\u011b toho zde samoz\u0159ejm\u011b hraje v pomal\u00e9m hojen\u00ed ran v\u00fdznamnou roli\u00a0 mikrobiom,<\/strong> proto\u017ee je zn\u00e1mo, \u017ee ko\u017en\u00ed a st\u0159evn\u00ed mikrobiom<\/strong> m\u00e1 zcela jin\u00e9 slo\u017een\u00ed a patogenn\u00ed z\u00e1rodky to zde tedy maj\u00ed snadn\u00e9.<\/p>

Diabetes 2. typu je dnes velmi roz\u0161\u00ed\u0159enou civiliza\u010dn\u00ed chorobou a diabetici se \u010dasto pot\u00fdkaj\u00ed s probl\u00e9my p\u0159i hojen\u00ed ran. Jak dlouho m\u016f\u017ee trvat hojen\u00ed otev\u0159en\u00e9 r\u00e1ny u diabetika a pro\u010d tomu tak je?<\/em><\/p>

Diabetick\u00e9 r\u00e1ny<\/strong> se hoj\u00ed velmi, velmi pomalu. Hoj\u00ed se stejn\u011b pomalu jako u pacient\u016f s poruchami krevn\u00edho ob\u011bhu,<\/strong> jednodu\u0161e proto, \u017ee tito pacienti maj\u00ed zhor\u0161enou obranyschopnost<\/strong> a hor\u0161\u00ed mikrocirkulaci v d\u016fsledku metabolick\u00e9ho syndromu.<\/strong> Zde je celkov\u00e1 imunita \u010dasto natolik oslabena, \u017ee je t\u0159eba t\u011blu pomoci zbavit se patogen\u016f v r\u00e1n\u011b \u010dastou v\u00fdm\u011bnou obvaz\u016f. To v\u0161ak samo o sob\u011b nen\u00ed v\u017edy dosta\u010duj\u00edc\u00ed a pro pacienty a o\u0161et\u0159ovatele ran to nen\u00ed v ka\u017edodenn\u00edm \u017eivot\u011b v\u017edy praktick\u00e9. Toto vedlo k nov\u00e9 my\u0161lence zapojen\u00ed mikrobiomu<\/strong> do procesu hojen\u00ed ran. Jeho vliv na zdrav\u00ed st\u0159ev<\/strong> je ji\u017e dob\u0159e zn\u00e1m. P\u0159itom st\u0159eva, sliznice a k\u016f\u017ee<\/strong> se svou strukturou a\u017e tak moc neli\u0161\u00ed. V\u0161echny jsou os\u00eddleny bakteriemi a mechanismy jsou na histologick\u00e9 a bun\u011b\u010dn\u00e9 \u00farovni podobn\u00e9. V\u00fdzkum st\u0159evn\u00ed bari\u00e9ry<\/strong> ji\u017e velmi pokro\u010dil a je z\u0159ejm\u00e9, \u017ee se zam\u011b\u0159uje na peror\u00e1ln\u00ed p\u0159\u00edjem probiotik. Kdo pou\u017e\u00edv\u00e1 probiotika na k\u016f\u017ei? Zde m\u016f\u017ee v\u00fdzkum bourat hranice, nebo\u0165 je z\u0159ejm\u00e9, \u017ee mechanismy mikrobiomu k\u016f\u017ee<\/strong> jsou velmi podobn\u00e9 t\u011bm ve st\u0159evech.<\/p><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Jakou roli hraj\u00ed probiotika p\u0159i hojen\u00ed ran?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Jakou roli mohou hr\u00e1t probiotika p\u0159i hojen\u00ed ran a jak\u00fd je zde sou\u010dasn\u00fd stav v\u011bdy – mohly by probiotick\u00e9 bakterie p\u0159\u00edpadn\u011b dokonce urychlit hojen\u00ed ran?<\/em><\/p>

V sou\u010dasn\u00e9 dob\u011b dokon\u010dujeme pilotn\u00ed studii<\/strong> o vlivu speci\u00e1ln\u00edho probiotika na hojen\u00ed ran a ji\u017e nyn\u00ed m\u016f\u017eeme sledovat ur\u010dit\u00fd trend. Zvolili jsme zde v\u00edcedruhov\u00e9 probiotikum<\/strong> speci\u00e1ln\u011b vyvinut\u00e9 pro diabetiky<\/strong> a metabolick\u00fd syndrom,<\/strong> proto\u017ee v\u0161ichni na\u0161i pacienti, kte\u0159\u00ed se studie \u00fa\u010dastnili, byli diabetici. Jedn\u00edm z kl\u00ed\u010dov\u00fdch zji\u0161t\u011bn\u00ed bylo, \u017ee u\u017e\u00edv\u00e1n\u00ed tohoto probiotika po dobu \u0161esti m\u011bs\u00edc\u016f vedlo ke zm\u011bn\u011b mikrobiomu k\u016f\u017ee<\/strong> a r\u00e1ny z patogenn\u00edch na m\u00e9n\u011b patogenn\u00ed. Toto zji\u0161t\u011bn\u00ed je p\u016fsobiv\u00e9 zejm\u00e9na proto, \u017ee pacienti u\u017e\u00edvali probiotika r\u00e1no ve sklenici vody – tedy peror\u00e1ln\u011b. Uk\u00e1zalo se, \u017ee probiotick\u00e9 bakterie si na\u0161ly cestu do k\u016f\u017ee a nakonec i do r\u00e1ny p\u0159es sliznici \u00fastn\u00ed dutiny a st\u0159eva.<\/strong> V ka\u017ed\u00e9m p\u0159\u00edpad\u011b je p\u016fsobiv\u00e9, \u017ee or\u00e1ln\u00ed p\u0159\u00edjem probiotik<\/strong> m\u00e1 pozitivn\u00ed vliv na ko\u017en\u00ed mikrobiom.<\/strong> Doufejme, \u017ee na toto t\u00e9ma budeme moci brzy prov\u00e9st rozs\u00e1hlej\u0161\u00ed studie, a jsem p\u0159esv\u011bd\u010dena, \u017ee se tyto \u00fa\u010dinky projev\u00ed i nad\u00e1le. V t\u00e9to pilotn\u00ed studii jsme tak\u00e9 mohli pozorovat, \u017ee u diabetik\u016f do\u0161lo k v\u00fdrazn\u00e9mu zlep\u0161en\u00ed paradent\u00f3zy,<\/strong> a to t\u00e9m\u011b\u0159 u v\u0161ech z\u00fa\u010dastn\u011bn\u00fdch. To bylo p\u016fsobiv\u00e9! Pokud si uv\u011bdom\u00edte, jak prob\u00edh\u00e1 b\u011b\u017en\u00e1 l\u00e9\u010dba parodontitidy – zdlouhav\u00e1, s mnoha n\u00e1v\u0161t\u011bvami zuba\u0159e, v\u00fdplachy \u00fast a bolestiv\u00fdm \u010di\u0161t\u011bn\u00edm – je u\u017e\u00edv\u00e1n\u00ed probiotik<\/strong> po dobu \u0161esti m\u011bs\u00edc\u016f snadn\u00fdm zp\u016fsobem, jak parodontitidu zlep\u0161it<\/strong><\/p>

Jin\u00fdmi slovy, probiotika<\/strong> rozhodn\u011b maj\u00ed vliv na k\u016f\u017ei a sliznice.<\/strong> T\u011b\u017eko \u0159\u00edci, do jak\u00e9 m\u00edry by jednou mohla b\u00fdt schopna nahradit antibiotika. P\u0159i pohledu do budoucnosti se domn\u00edv\u00e1m, \u017ee probiotika budou dal\u0161\u00edm n\u00e1strojem v l\u00e9\u010db\u011b chronick\u00fdch ran a probiotika budou d\u016fle\u017eit\u00e1 zejm\u00e9na u tlej\u00edc\u00edch infekc\u00ed.<\/strong><\/p>

Jak jste p\u0159i\u0161la na to, \u017ee by probiotika mohla hr\u00e1t roli p\u0159i hojen\u00ed ran?<\/em><\/p>

P\u0159ibli\u017en\u011b p\u0159ed t\u0159emi lety moje v\u00fdzkumn\u00e1 skupina publikovala studii, ve kter\u00e9 jsme v laborato\u0159i zkoumali vliv probiotick\u00fdch bakteri\u00ed na lidsk\u00e9 patogeny v bakteri\u00e1ln\u00edm biofilmu.<\/strong> Jin\u00fdmi slovy, pou\u017eili jsme krevn\u00ed plazmu, imunitn\u00ed bu\u0148ky a bakterie k vytvo\u0159en\u00ed biofilmu podobn\u00e9ho tomu, kter\u00fd se nach\u00e1z\u00ed na chronick\u00fdch ran\u00e1ch. Pot\u00e9 jsme testovali, zda r\u016fzn\u00e1 probiotika mohou tento biofilm a bakterie v n\u011bm zni\u010dit. K m\u00e9mu p\u0159ekvapen\u00ed dok\u00e1zala bakterie Lactobacillus plantarum<\/em><\/strong> zab\u00edt jednu z nejagresivn\u011bj\u0161\u00edch ko\u017en\u00edch bakteri\u00ed, Pseudomonas aeruginosa<\/em>, a potla\u010dit r\u016fst bakteri\u00ed Staphylococcus aureus.<\/em> Tato pozorov\u00e1n\u00ed byla p\u016fvodn\u011b pouze experiment\u00e1ln\u00edho charakteru, provedena ale v lidsk\u00e9m prost\u0159ed\u00ed, tedy v bl\u00edzkosti skute\u010dn\u00e9ho lidsk\u00e9ho biofilmu.<\/strong> B\u011bhem tohozo zkoum\u00e1n\u00ed jsme si uv\u011bdomili velk\u00fd potenci\u00e1l probiotik, i kdy\u017e v p\u0159\u00edpad\u011b chronick\u00fdch ran je st\u00e1le co zkoumat, zejm\u00e9na v\u00fdznam „dobr\u00fdch“ bakteri\u00ed. Lactobacillus plantarum<\/em><\/strong> v\u0161ak ur\u010dit\u011b m\u016f\u017eeme velmi dob\u0159e vyu\u017e\u00edt.<\/p>

Zejm\u00e9na zvy\u0161uje kyselost pH v r\u00e1n\u011b,<\/strong> co\u017e se typick\u00fdm p\u016fvodc\u016fm infekc\u00ed v r\u00e1n\u011b v\u016fbec nel\u00edb\u00ed. Je to trochu jako David a Goli\u00e1\u0161. Co se t\u00fd\u010de probl\u00e9mu infekc\u00ed v r\u00e1n\u011b, m\u00e1me co do \u010din\u011bn\u00ed s velmi agresivn\u00edmi bakteriemi,<\/strong> kter\u00fdm \u010del\u00ed mnoho p\u0159\u00e1telsk\u00fdch mal\u00fdch bakteri\u00ed, kter\u00e9 se takto mohou p\u0159emno\u017eit a mo\u017en\u00e1 i zv\u00edt\u011bzit.<\/p><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\n \"\" <\/div>\n <\/div>\n
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\n Prof. Dr. Ewa Klara St\u00fcrmer vystudovala medic\u00ednu na univerzit\u00e1ch v Essenu a G\u00f6ttingenu. Pracuje jako specialistka v oboru chirurgie, ortopedie a \u00farazov\u00e9 chirurgie, doktor\u00e1t z\u00edskala v roce 1996, v roce 2009 se habilitovala na Univerzit\u011b Georga Augusta v G\u00f6ttingenu a nyn\u00ed je vedouc\u00ed chirurgick\u00e9ho odd\u011blen\u00ed Komplexn\u00edho centra pro l\u00e9\u010dbu ran a transla\u010dn\u00ed v\u00fdzkum ran v Univerzitn\u00edm l\u00e9ka\u0159sk\u00e9m centru v Hamburku-Eppendorfu (UKE). <\/div>\n <\/div>\n <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

\u00dactyhodn\u00e9 \u010d\u00edslo: P\u0159ibli\u017en\u011b 90 % mikroorganism\u016f na na\u0161\u00ed k\u016f\u017ei tvo\u0159\u00ed bakterie. Stejn\u011b jako ve st\u0159evech, i zde jsou zastoupeny „dobr\u00e9“ a „\u0161kodliv\u00e9“ bakterie, p\u0159i\u010dem\u017e druh\u00e1 skupina se st\u00e1v\u00e1 probl\u00e9mem zejm\u00e9na v p\u0159\u00edpad\u011b rozs\u00e1hl\u00fdch nebo hlubok\u00fdch ran, kde naru\u0161uj\u00ed jejich hojen\u00ed. Prvn\u00ed v\u00fdzkumy v\u0161ak ukazuj\u00ed, \u017ee vhodn\u00e9 prosp\u011b\u0161n\u00e9 bakterie mohou poskytnout nov\u00fd terapeutick\u00fd p\u0159\u00edstup: O l\u00e9\u010db\u011b ran a o tom, jakou roli by zde mohla hr\u00e1t probiotika, jsme hovo\u0159ili s profesorkou Ewou Kl\u00e1rou St\u00fcrmerovou.<\/p>\n","protected":false},"author":13,"featured_media":18096,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[107],"tags":[],"class_list":["post-18000","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-novinky-ve-vyzkumu"],"acf":[],"rank_math":{"og:title":"Mohou probiotick\u00e9 bakterie pomoci p\u0159i hojen\u00ed ran?","og:desc":"Hojen\u00ed ran, a to zejm\u00e9na u diabetick\u00fdch pacient\u016f, je velk\u00fdm t\u00e9matem. Pro\u010d se n\u011bkter\u00e9 r\u00e1ny nehoj\u00ed a jakou roli zde mohou hr\u00e1t probiotick\u00e9 bakterie?","og:url":"https:\/\/www.omni-biotic.com\/cs-cz\/blog\/probioticke-bakterie-pri-hojeni-ran\/","og:locale":"cs_CZ","og:image":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-content\/uploads\/sites\/8\/2023\/11\/CZ_Blog_Bakterie-1.jpg","og:image:width":"700","og:image:height":"500"},"additional_data":{"thumbnail":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-content\/uploads\/sites\/8\/2023\/11\/CZ_Blog_Bakterie-1.jpg"},"blog_info":{"country":"cs-cz"},"_links":{"self":[{"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/posts\/18000","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/comments?post=18000"}],"version-history":[{"count":7,"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/posts\/18000\/revisions"}],"predecessor-version":[{"id":18281,"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/posts\/18000\/revisions\/18281"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/media\/18096"}],"wp:attachment":[{"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/media?parent=18000"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/categories?post=18000"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/tags?post=18000"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}