{"id":18986,"date":"2024-07-29T16:34:09Z","date_gmt":"2024-07-29T14:34:09Z","guid":{"rendered":"https:\/\/www.omni-biotic.com\/cs-cz\/?p=18986"},"modified":"2024-07-29T16:36:31Z","modified_gmt":"2024-07-29T14:36:31Z","slug":"kolonoskopie-a-mikrobiom-blog","status":"publish","type":"post","link":"https:\/\/www.omni-biotic.com\/cs-cz\/blog\/kolonoskopie-a-mikrobiom-blog\/","title":{"rendered":"Kolonoskopie a mikrobiom"},"content":{"rendered":"\t\t
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Kolonoskopie<\/strong> je endoskopick\u00e9 vy\u0161et\u0159en\u00ed tlust\u00e9ho st\u0159eva<\/strong> a toto ozna\u010den\u00ed poch\u00e1z\u00ed ze slov \u201ecolon\u201c (= st\u0159edn\u00ed \u010d\u00e1st tlust\u00e9ho st\u0159eva) a \u201escopie\u201c (= d\u00edvat se, zkoumat). Historie kolonoskopie za\u010d\u00edn\u00e1 v 60. letech 20. stolet\u00ed, kdy byl na Tokijsk\u00e9 univerzit\u011b vyvinut p\u0159\u00edstroj, kter\u00fd umo\u017e\u0148uje prohl\u00ed\u017eet st\u0159evo zevnit\u0159.<\/p>

Kolonoskopie dok\u00e1\u017ee odhalit a objasnit z\u00e1n\u011bty, polypy<\/strong> a zm\u011bny tk\u00e1n\u011b<\/strong> a\u017e po rakovinu st\u0159eva<\/strong> v ran\u00e9m stadiu.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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P\u0159ibli\u017en\u011b p\u0159ed 50 lety vyvinul \u0161v\u00fdcarsk\u00fd gastroenterolog Peter Deyhle postup pro odstran\u011bn\u00ed polyp\u016f tlust\u00e9ho st\u0159eva v r\u00e1mci kolonoskopie. Dnes se toto preventivn\u00ed vy\u0161et\u0159en\u00ed<\/strong> doporu\u010duje v\u0161em lidem ve v\u011bku kolem 50 let,<\/strong> aby se krom\u011b tlust\u00e9ho st\u0159eva<\/strong> prohl\u00e9dlo tak\u00e9 n\u011bkolik posledn\u00edch centimetr\u016f tenk\u00e9ho st\u0159eva.<\/strong><\/p>

D\u016fvodem jsou l\u00e9ky, pr\u016fmyslov\u011b zpracovan\u00e9 potraviny a negativn\u00ed vlivy vn\u011bj\u0161\u00edho prost\u0159ed\u00ed, stejn\u011b jako genetick\u00e9 predispozice, kter\u00e9 mohou v\u00e9st k r\u016fzn\u00fdm pot\u00ed\u017e\u00edm. B\u011bhem kolonoskopie<\/strong> m\u016f\u017ee l\u00e9ka\u0159 nejen vy\u0161et\u0159it cel\u00e9 tlust\u00e9 st\u0159evo,<\/strong> ale tak\u00e9 odebrat vzorky tk\u00e1n\u011b<\/strong> a prov\u00e9st drobn\u00e9 z\u00e1kroky.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Pro\u010d je kolonoskopie tak d\u016fle\u017eit\u00e1?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Kolonoskopie m\u016f\u017ee odhalit a objasnit z\u00e1n\u011bty, polypy a zm\u011bny tk\u00e1n\u011b<\/strong> a\u017e po rakovinu st\u0159eva<\/strong> v ran\u00e9m stadiu. P\u0159esto se mnoho lid\u00ed tomuto d\u016fle\u017eit\u00e9mu preventivn\u00edmu vy\u0161et\u0159en\u00ed st\u00e1le vyh\u00fdb\u00e1 – v sou\u010dasn\u00e9 dob\u011b ho vyu\u017e\u00edv\u00e1 jen asi 40 % populace. Strach z tohoto vy\u0161et\u0159en\u00ed je v\u0161ak neopodstatn\u011bn\u00fd, proto\u017ee kolonoskopii prov\u00e1d\u011bj\u00ed pouze l\u00e9ka\u0159i se specializovan\u00fdm zam\u011b\u0159en\u00edm,<\/strong> obvykle gastroenterologov\u00e9.<\/strong> Obecn\u011b je kolonoskopie bezpe\u010dn\u00fd a bezbolestn\u00fd z\u00e1krok s velmi n\u00edzk\u00fdm rizikem komplikac\u00ed – a trv\u00e1 m\u00e9n\u011b ne\u017e p\u016fl hodiny. Alternativn\u011b je mo\u017en\u00e9 st\u0159evo vy\u0161et\u0159it tak\u00e9 pomoc\u00ed tzv. kapslov\u00e9 endoskopie<\/strong> (kdy se spolkne mal\u00e1 kapsle s integrovanou kamerou) nebo zevn\u00edm vy\u0161et\u0159en\u00edm pomoc\u00ed po\u010d\u00edta\u010dov\u00e9 tomografie (CT)<\/strong> nebo magnetick\u00e9 rezonance (MRI)<\/strong>. Tyto alternativy jsou v\u0161ak n\u00e1kladn\u011bj\u0161\u00ed a\/nebo \u010dasov\u011b n\u00e1ro\u010dn\u011bj\u0161\u00ed – a kolonoskopie se prov\u00e1d\u00ed za \u00fa\u010delem odb\u011bru vzorku tk\u00e1n\u011b nebo odstran\u011bn\u00ed polyp\u016f a podobn\u011b, tak\u017ee m\u016f\u017eeme \u0159\u00edci, \u017ee kolonoskopie je efektivn\u00edm vy\u0161et\u0159en\u00edm<\/strong> 2 v 1.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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P\u0159\u00edprava na kolonoskopii<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Aby bylo mo\u017en\u00e9 st\u0159evo dob\u0159e vy\u0161et\u0159it, je nutn\u00e9, aby bylo zcela vypr\u00e1zdn\u011bn\u00e9.<\/strong> To vy\u017eaduje kr\u00e1tk\u00fd p\u016fst,<\/strong> kter\u00fd, jak se dozv\u00edte pozd\u011bji, m\u016f\u017ee m\u00edt i \u0159adu v\u00fdhod. 24 hodin p\u0159ed z\u00e1krokem<\/strong> se ji\u017e nesm\u00ed konzumovat \u017e\u00e1dn\u00e1 t\u011b\u017eko straviteln\u00e1 strava<\/strong> a posledn\u00edm<\/strong> pevn\u00fdm j\u00eddlem<\/strong> by m\u011bl b\u00fdt ob\u011bd<\/strong>\u00a0 jeden den p\u0159ed kolonoskopi\u00ed.<\/strong> Pot\u00e9 je povolen pouze v\u00fdvar, \u010daj a voda. N\u011bkolik dn\u00ed p\u0159edt\u00edm je t\u0159eba vyhnout se<\/strong> zejm\u00e9na potravin\u00e1m obsahuj\u00edc\u00edm obiloviny,<\/strong> kter\u00e9 maj\u00ed tendenci se usazovat ve st\u0159evn\u00ed st\u011bn\u011b. V p\u0159\u00edpad\u011b, \u017ee je st\u0159evo celkov\u011b pomalej\u0161\u00ed,\u00a0<\/strong>m\u016f\u017ee b\u00fdt prosp\u011b\u0161n\u00e9 zah\u00e1jit kr\u00e1tkodobou zm\u011bnu stravy je\u0161t\u011b d\u0159\u00edve.<\/strong><\/p><\/div><\/div><\/div>

Je tak\u00e9 nutn\u00e1 d\u016fkladn\u00e1 o\u010dista st\u0159ev.<\/strong> To je velmi d\u016fle\u017eit\u00e1, proto\u017ee stav st\u0159evo lze spolehliv\u011b prohl\u00e9dnout pouze tehdy, kdy\u017e je zcela pr\u00e1zdn\u00e9. K tomuto \u00fa\u010delu se pou\u017e\u00edv\u00e1 proj\u00edmadlo, tzv. st\u0159evn\u00ed lav\u00e1\u017e<\/strong> – a krom\u011b technick\u00e9ho pokroku do\u0161lo i zde ke zlep\u0161en\u00ed: \u201eKdy\u017e si vzpomenu na dobu p\u0159ed 30 lety, lid\u00e9 museli p\u0159ij\u00edt brzy r\u00e1no nebo uprost\u0159ed noci a vyp\u00edt \u0161est litr\u016f vodn\u00e9ho roztoku. Dnes je to omezeno na p\u0159ibli\u017en\u011b dva litry rozlo\u017een\u00e9 do dvou dn\u016f. To je mnohem p\u0159\u00edjemn\u011bj\u0161\u00ed,\u201c vysv\u011btluje st\u0159evn\u00ed specialista Prof. Dr. Joachim Labenz<\/strong> z Diakonie Klinikum Jung-Stilling v n\u011bmeck\u00e9m Siegenu.<\/p>

V\u00fdrazn\u00e9 sn\u00ed\u017een\u00ed nutn\u00e9ho u\u017eit\u00ed proj\u00edmadel, zv\u00fd\u0161ilo vst\u0159\u00edcnost pacient\u016f. \u201eOsobn\u011b to pova\u017euji za v\u00fdznamn\u00fd pokrok, m\u00e1me nyn\u00ed i mnohem v\u00edce l\u00e9ka\u0159\u016f,s vysokou kvalifikac\u00ed a \u010derpaj\u00ed ze zku\u0161enost\u00ed, co\u017e v\u00fdrazn\u011b sn\u00ed\u017eilo riziko komplikac\u00ed.\u201c<\/p>

Cel\u00fd proces p\u0159\u00edpravy prob\u00edh\u00e1 samoz\u0159ejm\u011b v \u00fazk\u00e9 konzultaci s o\u0161et\u0159uj\u00edc\u00edm l\u00e9ka\u0159em.<\/strong> L\u00e9ka\u0159 by m\u011bl b\u00fdt tak\u00e9 informov\u00e1n tak\u00e9 v p\u0159\u00edpad\u011b, \u017ee se pravideln\u011b u\u017e\u00edv\u00e1te l\u00e9ky,<\/strong> proto\u017ee laxace m\u016f\u017ee ovlivnit jejich \u00fa\u010dinek. N\u011bkter\u00e9 l\u00e9ky, nap\u0159. s obsahem l\u00e1tek na \u0159ed\u011bn\u00ed krve, m\u016f\u017ee b\u00fdt nutn\u00e9 p\u0159ed kolonoskopi\u00ed vysadit.<\/strong><\/p>

Pokud zva\u017eujete\u00a0v\u00fdhody a p\u0159\u00edpadn\u00e9 nev\u00fdhody kolonoskopie,<\/strong> p\u0159\u00edprava nen\u00ed velk\u00fdm probl\u00e9mem a ani p\u0159ek\u00e1\u017ekou.<\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Kolonoskopie - trval\u00fd pokrok<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Kolonoskopie je obvykle zcela bezbolestn\u00e1.<\/strong> Pro mnoho lid\u00ed je v\u0161ak pohodln\u011bj\u0161\u00ed, kdy\u017e si vy\u0161et\u0159en\u00ed neuv\u011bdomuj\u00ed. Ur\u010dit\u00e1 m\u00edra nehybnosti pacienta je pro l\u00e9ka\u0159e tak\u00e9 v\u00fdhodou, proto\u017ee samovoln\u00e9 nebo prudk\u00e9 pohyby by mohou v\u00e9st k drobn\u00fdm poran\u011bn\u00edm. \u201eProto se dnes kolonoskopie obvykle prov\u00e1d\u00ed pod lehkou sedac\u00ed. To znamen\u00e1, \u017ee samotn\u00e9 vy\u0161et\u0159en\u00ed ji\u017e nen\u00ed pro pacienta nep\u0159\u00edjemn\u00e9,<\/strong>\u201c dod\u00e1v\u00e1 gastroenterolog Prof. Dr. Labenz.<\/p>

P\u0159i kolonoskopii je pacient ulo\u017een do pohodln\u00e9 polohy<\/strong> na boku a kolonoskop, kter\u00fd se podob\u00e1 tenk\u00e9 ohebn\u00e9 trubi\u010dce, se pak pomoc\u00ed lubrikantu zavede do kone\u010dn\u00edku. Do st\u0159eva se vh\u00e1n\u00ed vzduch, aby se vyhladily st\u0159evn\u00ed z\u00e1hyby<\/strong> a bylo mo\u017en\u00e9 l\u00e9pe vid\u011bt i ty nejmen\u0161\u00ed zm\u011bny. Mnoz\u00ed l\u00e9ka\u0159i, jako nap\u0159\u00edklad profesor Dr. Labenz, zde tak\u00e9 vyu\u017e\u00edvaj\u00ed pokro\u010dilou alternativu. \u201eDal\u0161\u00edm v\u00fdvojem, kter\u00fd \u010din\u00ed vy\u0161et\u0159en\u00ed pro pacienta pohodln\u011bj\u0161\u00edm, je u\u017eit\u00ed CO2 m\u00edsto vzduchu.\u00a0<\/strong>T\u011blo toti\u017e CO2 odbour\u00e1v\u00e1 mnohem rychleji a d\u00edky tomu pacienti nemaj\u00ed po vy\u0161et\u0159en\u00ed tak v\u00fdrazn\u011b nafoukl\u00e9 b\u0159icho, co\u017e je pro mnoh\u00e9 velmi nep\u0159\u00edjemn\u00e9. To se d\u00e1 d\u00edky pou\u017eit\u00ed CO2 se to d\u00e1 v\u00fdrazn\u011b omezit.\u201c<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Hightech vybaven\u00ed a vy\u0161et\u0159en\u00ed v\u0161e v jednom<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Kolonoskop,<\/strong> kter\u00fd umo\u017e\u0148uje osv\u011btlen\u00ed a p\u0159enos obrazu, je pak velmi opatrn\u011b veden cel\u00fdm tlust\u00fdm st\u0159evem.<\/strong> L\u00e9ka\u0159 v\u0161e sleduje na monitoru a prohl\u00ed\u017e\u00ed celou vnit\u0159n\u00ed st\u011bnu st\u0159eva.<\/strong> Po vy\u0161et\u0159en\u00ed lze st\u0159evn\u00ed sliznici podrobn\u011bji analyzovat pomoc\u00ed zaznamenan\u00fdch sn\u00edmk\u016f. Pokud se ve st\u0159evn\u00ed st\u011bn\u011b objev\u00ed n\u011bjak\u00e9 abnormality, m\u016f\u017ee l\u00e9ka\u0159 ihned odebrat vzorky pomoc\u00ed mal\u00fdch kle\u0161t\u00ed a nechat je analyzovat v laborato\u0159i. \u00dast\u0159edn\u00edm \u00fakolem kolonoskopie<\/strong> je zejm\u00e9na odhalen\u00ed<\/strong> tzv. polyp\u016f.<\/strong> Polypy jsou v\u00fdr\u016fstky sliznice v tlust\u00e9m st\u0159ev\u011b a jsou samy o sob\u011b ne\u0161kodn\u00e9. Mohou ale ob\u010das vy\u00fastit v rakovinu st\u0159eva,<\/strong> a proto je v\u010dasn\u00e9 odstran\u011bn\u00ed velmi \u017e\u00e1douc\u00ed.<\/strong><\/p>

\u201eV odhalov\u00e1n\u00ed polyp\u016f<\/strong> jsme zaznamenali velk\u00e9 pokroky,<\/strong> \u010d\u00e1ste\u010dn\u011b d\u00edky zdokonalen\u00e9 technologii a \u010d\u00e1ste\u010dn\u011b d\u00edky rostouc\u00edm zku\u0161enostem l\u00e9ka\u0159sk\u00e9ho t\u00fdmu a v budoucnu<\/strong> by se mohla vyu\u017e\u00edvat tak\u00e9 um\u011bl\u00e1 inteligence.<\/strong> Stroje a programy, kter\u00e9 l\u00e9ka\u0159\u016fm pomohou odhalit velmi mal\u00e9 polypy zv\u00fd\u0161\u00ed po\u010det v\u010das odhalen\u00fdch polyp\u016f pro preventivn\u00ed odstran\u011bn\u00ed.<\/strong> Ani minim\u00e1ln\u00ed riziko poopera\u010dn\u00edho krv\u00e1cen\u00ed p\u0159i odstra\u0148ov\u00e1n\u00ed polyp\u016f nen\u00ed probl\u00e9m, proto\u017ee krv\u00e1cen\u00ed lze jednodu\u0161e zastavit.\u201c<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Za t\u00edmto \u00fa\u010delem kolonoskop obsahuje mal\u00e9 smy\u010dky s kan\u00e1lem,<\/strong> kter\u00e9 jsou vedeny kolem polyp\u016f a odd\u011bluj\u00ed je. To je obvykle tak\u00e9 zcela bezbolestn\u00e9. Samotn\u00e1 kolonoskopie trv\u00e1 obvykle m\u00e9n\u011b ne\u017e p\u016fl hodiny a prov\u00e1d\u00ed se ambulantn\u011b.<\/strong> Hospitalizace je nutn\u00e1 pouze ve v\u00fdjime\u010dn\u00fdch p\u0159\u00edpadech. Po dokon\u010den\u00ed vy\u0161et\u0159en\u00ed je sonda opatrn\u011b odstran\u011bna a je mo\u017en\u00e9 se hned naj\u00edst a pokra\u010dovat v b\u011b\u017en\u00e9m denn\u00edm rytmu.<\/strong> Na cest\u011b dom\u016f se doporu\u010duje doprovod d\u016fv\u011bryhodn\u00e9 osoby, proto\u017ee \u0159\u00edzen\u00ed dopravn\u00edho prost\u0159edku (automobilu, motocyklu, j\u00edzdn\u00edho kola) nen\u00ed vzhledem k lehk\u00e9 sedaci povoleno.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Co m\u00e1 kolonoskopie spole\u010dn\u00e9ho s mikrobiomem?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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O\u010dista tlust\u00e9ho st\u0159eva<\/strong> do\u010dasn\u011b vede k v\u00fdrazn\u00e9 zm\u011bn\u011b p\u0159irozen\u00e9 st\u0159evn\u00ed mikrofl\u00f3ry.<\/strong> <\/a>Od doby, kdy se v\u011bda dozv\u011bd\u011bla v\u00edce o \u00fast\u0159edn\u00edm v\u00fdznamu a citlivosti lidsk\u00e9ho mikrobiomu,<\/strong><\/a> jsou proj\u00edmadla u\u017e\u00edv\u00e1na \u0161etrn\u011bji. P\u0159esto je st\u0159evn\u00ed mikrofl\u00f3ra<\/strong> b\u011bhem p\u0159\u00edpravy na koloskopii decimov\u00e1na. D\u016fle\u017eit\u00fd pod\u00edl bakteri\u00ed,<\/strong> <\/a>kter\u00e9 jsou zodpov\u011bdn\u00e9 za na\u0161e tr\u00e1ven\u00ed<\/a> <\/strong>a imunitn\u00ed syst\u00e9m<\/a><\/strong>, je do\u010dasn\u011b vym\u00fdcena a tr\u00e1ven\u00ed ji\u017e nefunguje spr\u00e1vn\u011b.<\/strong> Absence dobr\u00fdch bakteri\u00ed tak\u00e9 umo\u017e\u0148uje patogen\u016fm mno\u017eit se ve st\u0159ev\u011b.<\/strong> Po kolonoskopii m\u016f\u017ee trvat i n\u011bkolik t\u00fddn\u016f nebo m\u011bs\u00edc\u016f, ne\u017e se st\u0159evn\u00ed mikrofl\u00f3ra zase d\u00e1 do po\u0159\u00e1dku. V\u00fd\u0161e zm\u00edn\u011bn\u00e1 zm\u011bna mikrobiomu je patrn\u00e1 a\u017e u 80 % pacient\u016f po kolonoskopii.<\/strong> T\u00e9m\u011b\u0159 polovina pacient\u016f trp\u00ed plynatost\u00ed,<\/strong><\/a> n\u00e1sledovanou pr\u016fjmem,<\/strong><\/a> bolestmi b\u0159icha<\/strong> a z\u00e1cpou.<\/a><\/strong> Pr\u00e1v\u011b to je d\u016fvodem, pro\u010d mnoz\u00ed odm\u00edtaj\u00ed podstoupit<\/strong> dal\u0161\u00ed kolonoskopii<\/strong> nebo toto vy\u0161et\u0159en\u00ed nepodstoup\u00ed v\u016fbec, kdy\u017e jim rodina a p\u0159\u00e1tel\u00e9 podrobn\u011b vypr\u00e1v\u011bj\u00ed o nep\u0159\u00edjemnostech, kter\u00e9 za\u017eili.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Kolonoskopie: V\u00fdhoda pro (nejen st\u0159evn\u00ed) zdrav\u00ed<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Kolonoskopie nen\u00ed jen d\u016fle\u017eit\u00fdm preventivn\u00edm vy\u0161et\u0159en\u00edm st\u0159ev. P\u0159\u00edprava na toto vy\u0161et\u0159en\u00ed m\u016f\u017ee m\u00edt pro mnoho z n\u00e1s tak\u00e9 v\u0161eobecn\u00fd zdravotn\u00ed p\u0159\u00ednos.<\/strong> Ve st\u0159ev\u011b se toti\u017e nach\u00e1zej\u00ed oblasti, nap\u0159\u00edklad v divertiklech<\/a><\/strong> (pozn. vn\u011bj\u0161\u00ed v\u00fd\u010dn\u011blky st\u0159eva, tj. opak polyp\u016f) nebo ve slep\u00e9m st\u0159ev\u011b, kde se mohou t\u00fddny a dokonce m\u011bs\u00edce hromadit v\u00fdkaly, kter\u00e9 zahn\u00edvaj\u00ed a zat\u011b\u017euj\u00ed st\u0159evo a organismus.<\/strong> Tyto zbytky tr\u00e1ven\u00ed se rovn\u011b\u017e odstra\u0148uj\u00ed p\u0159i st\u0159evn\u00ed lav\u00e1\u017ei. <\/strong>\u201ePodle m\u00e9ho pozorov\u00e1n\u00ed u pacient\u016f s divertikly v\u017edy platilo, \u017ee p\u0159\u00edprava na kolonoskopii<\/strong> jim \u010dasto prosp\u00edv\u00e1. M\u00e1m pacienty, kte\u0159\u00ed ji dobrovoln\u011b podstupuj\u00ed dvakr\u00e1t ro\u010dn\u011b, a to bez pozd\u011bj\u0161\u00ed kolonoskopie. Pot\u00e9 uv\u00e1d\u011bj\u00ed, \u017ee se c\u00edt\u00ed mnohem l\u00e9pe po dobu n\u011bkolika t\u00fddn\u016f nebo dokonce m\u011bs\u00edc\u016f,\u201c vysv\u011btluje odborn\u00edk.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Probiotika \u2013 \u00faleva a zlep\u0161en\u00ed p\u0159i a po koloskopii?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Prof. Dr. Labenz se tak\u00e9 zab\u00fdv\u00e1 souvislost\u00ed<\/strong> mezi p\u0159\u00edpravou na kolonoskopii, st\u0159evn\u00ed mikrofl\u00f3rou a st\u0159evn\u00edmi pot\u00ed\u017eemi<\/a>.<\/strong> Proto byla provedena klinick\u00e1 studie: \u201eJe naprosto jasn\u00e9, \u017ee p\u0159i v\u00fdplachu tlust\u00e9ho st\u0159eva<\/strong> doch\u00e1z\u00ed k ovlivn\u011bn\u00ed mikrobiomu.<\/strong> A proto m\u00e1 smysl u\u017e\u00edvat po kolonoskopii probiotika<\/a><\/strong> aby se zv\u00fd\u0161ila diverzita, tedy rozmanitost<\/strong> – a t\u00edm i funk\u010dnost<\/strong> – st\u0159evn\u00edho mikrobiomu.<\/strong><\/p>

Proto jsme po dobu \u010dty\u0159 t\u00fddn\u016f<\/strong> zji\u0161\u0165ovali, zda trp\u00ed pacienti po kolonoskopii pot\u00ed\u017eemi a zda jsou tyto pot\u00ed\u017ee odli\u0161n\u00e9 p\u0159i u\u017e\u00edv\u00e1n\u00ed placeba<\/strong> a p\u0159i u\u017e\u00edv\u00e1n\u00ed probiotika.<\/strong> Analyzovali jsme slo\u017een\u00ed st\u0159evn\u00ed mikrofl\u00f3ry<\/strong> pomoc\u00ed dne\u0161n\u00edch modern\u00edch metod, abychom zjistili, zda maj\u00ed probiotika vliv na diverzitu mikrobiomu,<\/strong> tedy na jeho rozmanitost. Ta je pova\u017eov\u00e1na za kvalitativn\u00ed vlastnost mikrobiomu – \u010d\u00edm je mikrobiom rozmanit\u011bj\u0161\u00ed, t\u00edm jste zdrav\u011bj\u0161\u00ed.<\/strong>\u201c<\/p>

V\u00fdsledky t\u00e9to aktu\u00e1ln\u00ed studie [1] jsou pozoruhodn\u00e9. Takzvan\u00e1 alfa diverzita,<\/strong> tedy rozmanitost mikrobiomu ve st\u0159ev\u011b p\u0159\u00edslu\u0161n\u00e9ho pacienta,<\/strong> byla toti\u017e ve skupin\u011b s probiotiky skute\u010dn\u011b v\u00fdznamn\u011b vy\u0161\u0161\u00ed<\/strong> ne\u017e ve skupin\u011b s placebem. Pozoruhodn\u00fd byl tak\u00e9 v\u00fdznamn\u011b zv\u00fd\u0161en\u00fd v\u00fdskyt<\/strong> jednoho z bakteri\u00e1ln\u00edch kmen\u016f<\/strong> obsa\u017een\u00fdch v u\u017e\u00edvan\u00e9m probiotiku.<\/p>

Pokud pro sebe chcete po koloskopii ud\u011blat n\u011bco dobr\u00e9ho, d\u00e1 se \u0159\u00edci: U\u017e\u00edvejte \u010dty\u0159i t\u00fddny speci\u00e1ln\u00ed probiotika, kter\u00e1 pomohou Va\u0161im st\u0159ev\u016fm a mikrobiomu.<\/p><\/blockquote>

Relevantn\u00ed je to zejm\u00e9na pro ty z n\u00e1s, kte\u0159\u00ed se dosud kolonoskopii vyh\u00fdbali<\/strong> kv\u016fli n\u00e1sledn\u00fdm mo\u017en\u00fdm za\u017e\u00edvac\u00edm probl\u00e9m\u016fm.<\/strong> U\u017e\u00edv\u00e1n\u00ed probiotik vedlo k v\u00fdrazn\u011b men\u0161\u00edmu po\u010dtu dn\u016f se z\u00e1cpou.<\/strong> Krom\u011b toho bylo zaznamen\u00e1no v\u00fdrazn\u011b m\u00e9n\u011b tr\u00e1vic\u00edch pot\u00ed\u017e\u00ed, jako je pr\u016fjem nebo plynatost.<\/strong><\/p>

\u201ePokud pro sebe chcete po kolonoskopii ud\u011blat n\u011bco dobr\u00e9ho, d\u00e1 se \u0159\u00edci: u\u017e\u00edvejte po dobu \u010dty\u0159 t\u00fddn\u016f speci\u00e1ln\u00ed probiotika, kter\u00e1 pomohou va\u0161im st\u0159ev\u016fm a va\u0161emu mikrobiomu. To je ur\u010dit\u011b z\u00e1v\u011br, kter\u00fd bych z \u00fadaj\u016f t\u00e9to studie vyvodil,\u201c zhodnocuje pozitivn\u011b profesor Dr. Labenz.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Zdroj:<\/strong><\/p>

[1] Labenz, J. et al. Ein Multispezies-Probiotikum zeigt einen positiven Effekt auf das intestinale Mikrobiom und reduziert Darmsymptome nach einer oralen Darmlavage zur Vorsorge-Koloskopie: randomisierte, doppelblinde, plazebokontrollierte Multicenterstudie (COLONIZE). Z Gastroenterol. 60(08): 643\u2013643 (2022) DOI 10.1055\/s-0042-1755100<\/p>

Profil odborn\u00edka:<\/strong><\/p>

Professor Dr. Joachim Labenz: Professor Dr. Joachim Labenz: Soukrom\u00e1 gastroenterologick\u00e1 a hepatologick\u00e1 ordinace na diakonii Klinikum Jung-Stilling, Siegen (N\u011bmecko), \u0158editel L\u00e9ka\u0159sk\u00e9 kliniky I<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Kolonoskopie je jedn\u00edm z nejd\u016fle\u017eit\u011bj\u0161\u00edch preventivn\u00edch vy\u0161et\u0159en\u00ed, kter\u00e9 udr\u017euje na\u0161e (st\u0159evn\u00ed) zdrav\u00ed a v\u010das odhaluje zm\u011bny tk\u00e1n\u00ed – v\u010detn\u011b nap\u0159\u00edklad rakoviny st\u0159ev. P\u0159esto\u017ee technick\u00fd a v\u011bdeck\u00fd v\u00fdvoj kolonoskopie ud\u011blal velk\u00fd pokrok, mnoho lid\u00ed se tomuto ne\u0161kodn\u00e9mu vy\u0161et\u0159en\u00ed st\u00e1le vyh\u00fdb\u00e1. Za\u017e\u00edvac\u00ed pot\u00ed\u017ee, kter\u00e9 osobn\u011b za\u017eili nebo o kter\u00fdch vypr\u00e1v\u011bla rodina a p\u0159\u00e1tel\u00e9, jsou \u010dasto d\u016fvodem, pro\u010d mnoz\u00ed z n\u00e1s kolonoskopii nepodstoup\u00ed. Kolonoskopie v\u0161ak neslou\u017e\u00ed pouze k v\u010dasn\u00e9mu odhalen\u00ed st\u0159evn\u00edch onemocn\u011bn\u00ed. S n\u00ed spojen\u00e9 nezbytn\u00e9 vypr\u00e1zdn\u011bn\u00ed st\u0159eva m\u016f\u017ee m\u00edt tak\u00e9 velk\u00fd zdravotn\u00ed p\u0159\u00ednos.<\/p>\n","protected":false},"author":13,"featured_media":19013,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[107,108],"tags":[],"class_list":["post-18986","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-novinky-ve-vyzkumu","category-potize-a-poradenstvi"],"acf":[],"rank_math":{"og:title":"Kolonoskopie a mikrobiom - OMNi-BiOTiC\u00ae Blog","og:desc":"Kolonoskopie je jedn\u00edm z vy\u0161et\u0159en\u00ed, kter\u00e9mu se \u010dasto sna\u017e\u00edme vyhnout. Pro\u010d se koloskopie nemus\u00edme b\u00e1t a jak\u00fd m\u00e1 vliv na n\u00e1\u0161 st\u0159evn\u00ed mikrobiom?","og:url":"https:\/\/www.omni-biotic.com\/cs-cz\/blog\/kolonoskopie-a-mikrobiom-blog\/","og:locale":"cs_CZ","og:image":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-content\/uploads\/sites\/8\/2024\/07\/Kolonoskopie.jpg","og:image:width":"768","og:image:height":"483"},"additional_data":{"thumbnail":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-content\/uploads\/sites\/8\/2024\/07\/Kolonoskopie.jpg"},"blog_info":{"country":"cs-cz"},"_links":{"self":[{"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/posts\/18986","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/comments?post=18986"}],"version-history":[{"count":7,"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/posts\/18986\/revisions"}],"predecessor-version":[{"id":19014,"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/posts\/18986\/revisions\/19014"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/media\/19013"}],"wp:attachment":[{"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/media?parent=18986"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/categories?post=18986"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.omni-biotic.com\/cs-cz\/wp-json\/wp\/v2\/tags?post=18986"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}