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Institut AllergoSan conquers global rankings

OMNi-BiOTiC®, the science-based probiotics brand, is now in the top 3 worldwide!

Graz, May 2023

It was a true pioneering spirit that drove Anita Frauwallner to embark on a largely unknown and risky path more than 30 years ago. Her focus on microbiome research and the development of innovative, high-quality probiotics led to the founding of Institut AllergoSan, and the creation of the probiotics brand OMNi-BiOTiC®, which is now number 1 in German-speaking countries as well as others.

The success of OMNi-BiOTiC® is continuing to spread around the globe, as the latest figures show[1] - in 2021, the brand was the 6th largest probiotics brand in the world, however, as of this year, OMNi-BiOTiC® is ranked 3rd globally!

"Thirty years ago, it was only important to me to help people to be able to live healthily and without restrictions with OMNi-BiOTiC®, however, I never considered that this would become a global brand," says Anita Frauwallner, founder and director of Institut AllergoSan. "The success is not only shown by our outstanding clinical evidence but also by the noticeable difference within a few days of using our products, these are the reasons why OMNi-BiOTiC® products inspire so many people worldwide," adds her son Bernd Assinger, Managing Director of Institut AllergoSan.

People in over 40 countries now benefit from using OMNi-BiOTiC® products. "It is therefore not surprising that OMNi-BiOTiC® is already considered a benchmark in the field of probiotics by experts and that the interest of potential new partners around the globe continues to grow," comments Christian Gsöll, Director of Business Development at Institut AllergoSan, who is looking forward to further opportunities for expansion in the future.

Today, the OMNi-BiOTiC® range comprises sixteen probiotics specifically formulated for different indications. These contain synergistic strains of bacteria carefully selected for their abilities to colonise the human gut. To massively increase the activity of these intestinal inhabitants, they are embedded in a matrix of enzymes and key substances. Institut AllergoSan is a recognised centre of excellence for microbiome research and is known worldwide for innovative and highly effective products that have won numerous international awards, including top rankings in the US, such as the NutraIngredients Award "Probiotic of the Year" [2].

More than 100 research papers have been published on OMNi-BiOTiC®, 48 studies are currently ongoing and the scientific track record in high-ranking peer-reviewed journals is outstanding. This ensures the sustained success of the OMNi-BiOTiC® brand through new developments that will continue to emerge in new medical fields in the years to come. Impressive study results combined with excellent training concepts, as well as a proven international marketing toolkit, also give new distributors the chance to quickly reach top rankings in their probiotic OTC market.

 "30 years ago, we set out to seek new possibilities in the field of preventive and natural medicine, which only a few specialists believed in at the time. 30 years later, we have now been able to help millions of people who put their trust in OMNi-BiOTiC® to noticeably improve their quality of life. We would like to continue on this path together with our committed team of employees, as we believe that it is possible, even from the small country of Austria, to achieve outstanding results at an international level when we combine the right ideas with our dedication and enthusiasm," sums up Anita Frauwallner, CEO of Institut AllergoSan.


[1] IQVIA Global OTC Insights - Local Currency Eur based on Public Price, Calender Year 2022 03F1 Probiotics Digest Health and 03D5 Antidiarr Micro-Organisms, IQVIA OTC audits


Hermes Business Award Winner!

hermes business award

Anita Frauwallner (right) received the award from Angelika Sery-Froschauer (WKÖ). (C) Mikes

Institut AllergoSan was awarded the HERMES Business Award as the best company run by a woman for the fourth time.

Graz, November 2022

The HERMES.Business.Award has been awarded for outstanding achievements in the Austrian economy for seven years. After 2017, 2018 and 20191, Institut AllergoSan can look forward to receiving this award as Austrian Business Champion for the fourth time in 2022.2 "It is a great honour to receive this prestigious award again. It clearly shows us that our products are more in tune with the spirit of the times than ever before. After all, health has taken on a new significance for many people in recent years," says a delighted Anita Frauwallner, founder and CEO of Institut AllergoSan.

The recipe for the continuing success: innovative product development, scientific research and noticeable quality. OMNi-BiOTiC® is quite rightly called the "benchmark in probiotics" in international expert circles - and this is also evident when looking at the market: in German-speaking Europe (Austria, Germany, Switzerland), OMNi-BiOTiC® has been number 13 for years, and among the probiotics brands with the highest sales worldwide, OMNi-BiOTiC® already occupies fourth place4 , and the trend is rising.

Frauwallner sees the award not only as an award for work done: "Every award is at the same time our incentive - because every person deserves the best possible quality of life and health, and that is what my team and I work for with full commitment.


3) IQVIA / sell-out by value as of end December 2021
4) IQVIA Global OTC Insights – Local Currency Eur based on Public Price, Calender Year 2021 03F1 Probiotics Digest Health and 03D5 Antidiarr Micro-Organisms, IQVIA OTC audits

Institut AllergoSan strengthens its global position

Mag. Anita Frauwallner, Mag. Bernd Assinger © Institut AllergoSan

OMNi-BiOTiC®, the evidence based probiotic brand, has jumped up two positions and is now number four worldwide!

Graz, 19.04.2021

30 years back, Anita Frauwallner faced lots of skepticism as she decided to set foot on a largely unknown and high-risk path of microbiome research and the development of innovative probiotic products. Her passion, research, and her dedication to the uttermost quality, combined with a large international network of renowned scientists, finally resulted in the founding of Institut AllergoSan and the creation of the probiotic brand OMNi-BiOTiC®, which meanwhile ranks as the number one probiotic within German-speaking Europe.

However, the success of OMNi-BiOTiC® is spreading around the globe – in 2021 the brand was ranked no. 6 (in pharmacy sell out) and at the beginning of 2022 it reached number 4 on the probiotic market worldwide [1].

“Among experts, OMNi-BiOTiC® is already considered as a benchmark in probiotics”, says Anita Frauwallner, Founder and CEO of Institut AllergoSan. “Excellent clinical research data paired with fast noticeable positive effects are the main reasons why OMNi-BiOTiC® enthuses so many customers and business partners worldwide”, adds Cornelia Schweinzer, responsible for International Business Relations at Institut AllergoSan. “Beside our subsidiaries in Germany, USA, Italy and Croatia, we are now represented by more than 25 countries worldwide - and the interest shown from potential new partners is only increasing”, comments Christian Gsöll, Director of Business Development at Institut AllergoSan.

Today the brand OMNi-BiOTiC® consists of fourteen medically relevant and indication specific probiotics which contain carefully selected synergistically acting bacterial strains of human origin embedded in an individually designed matrix based on the strains' needs to sustain their activity and function. Institut AllergoSan is a recognised competence center for microbiome research and is well known worldwide for innovative and state of the art products which are highly awarded, such as recently with the US NutraIngredients Award for the category “Probiotic of the Year 2021” [2].

Currently more than 40 clinical studies are ongoing, more than 100 studies have been conducted and the scientific track record in high-ranked peer-reviewed journals is outstanding. This ensures our further portfolio expansion and the success of OMNi-BiOTiC®. These incredible study results combined with excellent educational concepts and a proven international marketing toolbox gives new distributors the chance to quickly gain top-positions in their local probiotic OTC market.

"Our story, which began 30 years ago in a small Austrian city, gives many founders in the healthcare sector the courage that - even in this highly competitive market - with outstanding commitment, the right ideas and, above all, personal enthusiasm, you can achieve outstanding results on an international level," summarises Anita Frauwallner, CEO Institut AllergoSan.


[1] IQVIA Global OTC Insights - Local Currency Eur based on Public Price, Calender Year 2021 03F1 Probiotics Digest Health and 03D5 Antidiarr Micro-Organisms, IQVIA OTC audits


Huge international success for OMNi-BiOTiC®

Award probiotic of the year 2021 nutraingredients

Photo credits: Institut AllergoSan / NutraIngredients USA

Austrian probiotic awarded product of the year in the USA

Graz, July 2021

One of the most important news sources for the industry, namely that of the highest quality dietary supplements, NutraIngredients-USA, has presented its awards for 2021, recognizing OMNi-BiOTiC® as the best probiotic product of the year [1].

Shortly after launching at the end of 2019, AllergoSan USA was able to win this internationally highly esteemed award for OMNi-BiOTiC® STRESS Release - known in Austrian pharmacies as OMNi-BiOTiC® STRESS Repair. As of 2021, the USA represents one of the world's largest markets in the field of dietary supplements. At the end of 2019, Anita Frauwallner decided to enter the land of opportunity with her successful probiotics brand OMNi-BiOTiC® (leading probiotics brand according to pharmacy sales in German-speaking Europe).

"After a start-up year in the USA that was strongly influenced by the pandemic, I am all the more pleased that the extraordinary quality and effectiveness of our OMNi-BiOTiC® products was recognized so quickly in the USA," says Frauwallner, CEO of Institut AllergoSan.

"This award is another milestone for us on our way to becoming a global brand," adds Frauwallner's son Bernd Assinger, co-owner of the family company.

In what is now the 30th year of the company's history, this award is not only particularly valuable for the company in making OMNi-BiOTiC® even better known internationally, but also confirms the excellence of the decades of research behind the brand. Thanks to collaborations with leading clinics in Europe and a network of microbiome experts around the globe, the company is today able to develop products that are regarded by many internationally as the "benchmark in probiotics".

"OMNi-BiOTiC® is now already among the six largest probiotics brands worldwide [2]. With this award we will further strengthen our path to spread high-quality probiotic medicine and the omnibiotic lifestyle throughout the world" - states Anita Frauwallner, founder of Institut AllergoSan, who is herself also involved in various organizations that focus on the importance of probiotic medicine.

[2] IQVATM Global OTC Insights - Local Currency Euro based on Public Price €M, MAT 12/2019, 03F1 PROBIOTICS DIGEST HEALTH/ A7F ANTIDIARR MICRO-ORGANISM, IQVIA OTC audits (Excl.Venezuela).

Graz-based Institut AllergoSan remains strong on their course for international expansion

OMNi-BiOTiC® is already among the top intestinal bacteria products worldwideinstitut allergosan anita frauwallner bernd assinger empfang erfolg probiotics

Graz, June 2021

When Anita Frauwallner started working with intestinal bacteria 30 years ago, no one would have thought that the OMNi-BiOTiC® brand she launched would go on to become the number one pharmacy brand in Austria and Germany in 2021, and to be among the top probiotic products worldwide. New subsidiaries in the USA, Italy, Croatia as well as new distribution partnerships in many other countries from Bulgaria to Taiwan allow the export team from Austria to continue its unstoppable run of success. "The interest in our top-quality probiotic products continues to be very high," explains Christian Gsöll, Director Business Development at Institut AllergoSan. "Not only the excellent clinical evidence, but also the quick, positively noticeable difference, are arguments that inspire many people and many partners from all over the world," adds Cornelia Schweinzer, who is responsible for International Business Relations. Having just returned from the largest health trade fair in the Middle East, Arab Health, the contact books are again full of new prospective customers from Africa to Asia.

The 14 probiotic products in the range, combined under the OMNi-BiOTiC® brand, represent one of the most comprehensive product portfolios in this field worldwide. This testifies to Institut AllergoSan’s innovative strength: as a competence centre for microbiome research and with its global network to numerous leading clinics and researchers in the gastroenterological field, it has a unique position. On this basis, Institut AllergoSan develops innovative products that are state of the art in this discipline. This is also confirmed by a recent nomination among the 3 best probiotic products of the year by Nutraingredients in the USA.

Anita Frauwallner’s mission is to make medically relevant probiotics a fixed part of our healthcare system, so that they are affordable for all. "Over the last 30 years, we have focused on the research and development of products made from natural substances such as probiotic bacteria, plant extracts and minerals with the aim of maintaining or restoring the health of our fellow human beings. In doing so, we are pursuing a holistic approach, namely, to strengthen the human health foundation before health problems arise - and to do so with what nature has provided for us,” explains Frauwallner. "Our clear future direction is to make OMNi-BiOTiC® products available globally. We are already on the right path!" adds Frauwallner's son Bernd Assinger, who privately owns Institut AllergoSan together with his mother. With the approximately 100 clinical studies that Institut AllergoSan is currently working on, a good foundation has been laid to remain successful on the world’s market with further innovations. "Our story, which began 30 years ago in Graz, gives many founders in the health sector the courage that with the right commitment, the right idea and, above all, the right enthusiasm, it is also possible to achieve outstanding results internationally in this highly competitive market," summarises Anita Frauwallner, CEO of Institut AllergoSan.

Institut AllergoSan: Managing Director on a health mission

Pressemeldung: Managing Director in gesundheitlicher MissionInstitut AllergoSan, including its brand OMNi-BiOTiC®, is continuously growing - not only in sales figures but also in manpower:

By hiring Mag. Thomas Perissutti, Institut AllergoSan found a highly-qualified Managing Director to play a decisive role in shaping a positive future for the company with his experience and expertise.

The former board member of Neuroth AG looks forward to his new assignment: "My personal motivation is to help people and improve their quality of life. That is why I am exceptionally proud to now be a part of Institut AllergoSan: As a centre of expertise in microbiome research, we play a pioneering role when it comes to medical research which, in turn, improves the health foundation of every individual."

Company founder and CEO, Mag. Anita Frauwallner is pleased about the competent support: "Thomas Perissutti not only convinced my son and me with his expertise but also with his personality - we both have a good "gut feeling" and know that together, we can forge ahead with our mission: By continuously improving many fields in medicine with the help of medically relevant probiotics, and by making a significant contribution to the wellbeing of every single person."


OMNi-BiOTiC again Germany's No 1 OTC Brand

Institut AllergoSan - awarded several times in Austria and Germany

Institut Allergosan was again able to shine at this year's inspirato Pharma Marketing Award: the Graz-based family business convinced the jury with its multi-award winning successful brand OMNi-BiOTiC® and secured its second victory in the category "OTC Brand of the Year". In addition, Institut Allergosan took the second place in the "OTC Company of the Year" category. But that's not all: at the same time the IQVIA Awards ceremony took place in Vienna, where Institut AllergoSan also achieved a top ranking. This is clear evidence of the increasing importance of medically relevant and indication-specific synbiotics.  

Yesterday, the inspirato Pharma Marketing Award was presented for the sixth time as part of the industry meeting “Pharma Marketing” in Bonn, Germany. The award honors the most successful OTC companies, brands and new launches of the year. Institut Allergosan was pleased with the victory by its successful synbiotics brand OMNi-BiOTiC® in the category "OTC Brand of the Year" - and this for the second time in a row. There was even more reason to celebrate with the second place in the category "OTC company of the year". The inspirato Pharma Marketing Award is based on the company's sales growth in 2017 as well as figures from the market research company Insight Health. In addition, the results of an online pharmacist survey are included in the evaluation. The final winners were selected by a jury consisting of industry representatives, agencies, consultants and retailers.

An outstanding award

The award also proves that the research and production of medically relevant, indication-specific synbiotics is playing an increasingly important role. "The ecosystem in our gut is so complex that we need different solutions for different clinical requirements. With our research work, we set new standards in the field of microbiome research and product development, "says Mag. Anita Frauwallner, founder and CEO of the Institut Allergosan. The secret behind the success of OMNi-BiOTiC®: the passion to develop products that set new standards in quality and that do not only treat symptoms, but also target the cause of the disease. This results in synbiotics that have a noticeable effect on the user and thus also trigger enthusiasm among people using OMNi-BiOTiC products.  

A "Victor" for the best

At the same time, the IQVIA Awards event was held at the 25hours Hotel in Vienna. For the first time, IQVIA, a global leader in human data science, awarded the Pharma Excellence Award "Victor. For this award a rating was used which was based on market share, growth, focus market, innovation and brand as well as product diversity. "In addition to being awarded the OTC Brand of the Year in Germany, we also achieved a top ranking in Austria in the new IQVIA Pharma Excellence Award. This confirms the path we have taken to ensure that the highest quality and innovation-oriented research work prevails on the market, "concludes Anita Frauwallner.

Probiotic therapy of liver function disorders with OMNi-BiOTiC® HETOX


Europe’s most innovative OTC-product comes from Austria

Sensational success for Institut Allergosan from Graz, Austria: The probiotic OMNi-BiOTiC® HETOX* was awarded the international Nicholas Hall Award as the Europe-wide OTC innovation of the year 2016.

30% of the population already suffer from liver problems and contrary to the popular belief that alcohol is the predominant cause of liver damage, the number of patients with non-alcoholic fatty liver disease is rising drastically. Consuming sugar, fat, numerous pharmaceuticals, but also being infected by various viruses can impair the function of our detoxification centre, the liver – and frighteningly often this leads to liver cancer.

Using a probiotic which was developed by Institut Allergosan from Graz (OMNi-BiOTiC® HETOX), a team from the Medical University of Graz under the supervision of Prof Vanessa Stadlbauer-Köllner could clearly show that several special gut bacteria influence liver function and the severity of infections. “During this placebo controlled study the liver function of the patients taking the probiotic improved significantly”, summarises Stadlbauer-Köllner.

International recognition for the cooperation in Graz

Hepatologists from around the world have showed great interest in the study: The study was presented at the renowned “Liver Week”, organised by the American Association for the Study of Liver Diseases (AASLD). Amongst the 10,000 submitted studies it was awarded the title “poster of distinction”.

Now the product has been awarded the renowned Nicholas Hall OTC Marketing Award for the Europe-wide OTC innovation of the year 2016: “This is a particularly great honour and a massive achievement for us” rejoices Mag. Anita Frauwallner, CEO of Institut Allergosan. “The fact that our product OMNi-BiOTiC® HETOX has received such praise concerning the therapy of liver diseases not only highlights the increasing importance of relevant probiotics. It is even more pleasing to see the international recognition our company is receiving; a company which has employed itself to studying the gut and its microbiome for 25 years. We have already shown on multiple occasions that gut bacteria positively influence the entire organism.”

Cornerstone ceremony of the internationally successful Institut Allergosan

One of Styrias figureheads, the company Institut Allergosan, is building a dazzling new headquarters in Graz, Austria

This impressive flagship of the pharmaceutical company Institut Allergosan is emerging in the south of Styrias capital and will stretch over an area of just under 12,500 square metres. On Thursday, the founder, and CEO Mag. Anita Frauwallner celebrated laying the foundation stone together with the mayor of Graz, Mag. Siegfried Nagl.

Personally, as well as in business matters, Anita Frauwallner is a devout Styrian and she proves this through her renewed commitment to this location. Although Institut Allergosan is an internationally active company, our roots clearly lie in the heart of Styria. It was here that we developed our ideas and visions; it is here that we will continue our research. Even a large portion of the over 100 employees, the people who made the probiotic specialist one of Austrias top pharmaceutical companies, are from Styria.

In fact, the company has become so big that there just wasnt enough space in their old location in Graz. Every year, the companys revenue has grown in double-digits. We started out as a single employee in 2002; meanwhile our team has grown to 115 employees, explains Frauwallner. We want to be able to offer our employees an inspiring work environment, that matches their exceptional dedication.

Starting with the buildings completion in autumn 2017, the employees will have access to the 6430 square metres of usable area which the 5-storey building will offer. There is a particular focus on the event centre, which will include a lecture hall for up to 260 people. Moreover, there will be seminar rooms and encounter zones on every floor.

The mayor of Graz, Siegfried Nagl, is also very pleased by the companys plans for a new headquarters. With their research and products, Anita Frauwallner and Institut Allergosan ensure that nothing can upset ones stomach too easily! Her ideas and innovations have an international impact, but ultimately, they ensure a workplace for many people in Graz.

Focus: Sustainability and theme-relevant architecture

The construction concept was drawn up by the East-Styrian planning department Architektur 64. The plan pays special attention to the greening of the roof and facade elements, as well as incorporating photovoltaic installations on the roof; these will deliver a substantial amount of the buildings energy demands. This reflects the sustainability of the companys philosophy. Moreover, the architects didnt forget Institut Allergosans central topic of interest: A highlight of the design is a coiled main staircase located in the foyer. It is a three-dimensional representation of the institutes main research field, the gut.

This house we are building, shouldnt only be used for work. For many, it will be a house of health, says Frauwallner. The new location will not only continue to be the development site for solutions to health issues. It will offer the possibility for visitors to experience lectures from renowned physicians and researchers. In these rooms, people should obtain inspiration on how to live long and healthy lives, says Frauwallner.


Relief for the liver – from the gut

Probiotic from Austrian research is a beacon of hope for people suffering from liver disease

More and more people suffer from liver diseases, especially the feared liver cirrhosis. For many patients this diagnosis means the beginning of a race against time, because at some point the damage to the liver is no longer reversible. Yet a dedicated cooperation between the Medical University of Graz and the competence centre for microbiome research at the institute Allergosan has achieved a breakthrough: A probiotic proves to be a beacon of hope for people suffering from liver disease.

30 % of the population already suffer from liver problems. Contrary to the popular belief that liver damage is primarily caused by alcohol, the number of patients suffering from non-alcoholic fatty liver disease is increasing at an alarming rate. Various viral diseases, but especially an excessive consumption of sugar, fat and numerous pharmaceuticals, can severely inhibit the function of our body’s detoxification centre.

What many people don’t realise is that the gut plays a key role in our liver’s health! A balanced intestinal flora and intact intestinal barrier are able to eliminate pathogens and toxic substances beforehand and so unburden the liver. However, if the intestinal mucosa is damaged (“leaky gut”), an increased amount of harmful substances can enter the blood steam via the portal vein. This blood vessel leads directly to the liver and so the liver is flooded with pathogenic substances. This overburdens the liver, causing blood congestion, hardening and often it can no longer fulfil its functions completely.

A cooperation in Graz: A probiotic improves liver function

Associate professor Vanessa Stadlbauer-Köllner’s team from the Medical University of Graz, tested a probiotic (OMNi-BiOTiC® HETOX*) developed by the institute Allergosan from Graz. With these results it could be shown for the first time ever, that extremely small gut bacteria can have a really big influence on liver function.

It was a placebo controlled, double blind study. 101 patients with liver cirrhosis, which were already being treated at the Graz university hospital’s department for gastroenterology and hepatology, were included in the study. Every day, for over the six months, the patients either took the specially developed probiotic or a placebo. Afterwards they were observed closely for another six months. “In this placebo controlled study, the liver function of those who took the probiotic improved significantly”, summarises professor Stadlbauer-Köllner.

Patients with liver cirrhosis generally exhibit increased susceptibility to infections. This makes it even more significant that parameters such as neopterin and respiratory burst, which are closely associated with increased immune activity, show a significantly positive trend under influence of the probiotic. This would also explain the lower infection rate during therapy in the group treated with the probiotic (15 vs 29 in the placebo group).

The tolerability of OMNi-BiOTiC® HETOX and the therapy adherence (98,9% of the doses were taken) were excellent in the probiotic group. In addition, no interactions with other medications were documented, which is especially important when treating high-risk patients such as these. It’s also interesting to note that only one patient from the probiotic group dropped out of the study before it was over, whereas there were 11 drop-outs in the placebo group. “That is notable evidence of an improved quality of life through the probiotic. The patients also claimed that they feel much more energetic and have more social contacts”, said Vanessa Stadlbauer-Köllner.

Mag. Anita Frauwallner, CEO and research director of the institute Allergosan: “The outstanding results of this study are trendsetting for modern medicine, in which microbiome research already plays a definitive role. It’s yet another milestone in our 25 years of work.”

Outstanding work

So far there have not been any therapeutic intervention options which could improve liver function in patients with liver cirrhosis. This study from Graz however, clearly shows that with the application of specially developed probiotics such as OMNi-BiOTiC® HETOX, an improvement of liver function is suddenly achievable. The international interest is immense: The study data was presented at the world’s largest hepatology congress, the renowned “Liver Week”, which is organised by the American Association for the Study of Liver Diseases (AASLD). Among the 10,000 submitted works, it was awarded the title “poster of distinction”.

Anita Frauwallner: “We were able to show that OMNi-BiOTiC® HETOX can contribute a large amount towards a healthy liver. On the one hand it targets the root of the problem, and more importantly, none of the serious side effects caused by medication ever arise during the application of probiotics. A crucial step towards a healthy future.”



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