{"id":21164,"date":"2023-10-17T17:31:26Z","date_gmt":"2023-10-17T15:31:26Z","guid":{"rendered":"https:\/\/www.omni-biotic.com\/sk-sk\/?p=21164"},"modified":"2025-03-06T13:41:58Z","modified_gmt":"2025-03-06T12:41:58Z","slug":"mozu-bakterie-pomahat-pri-hojeni-ran","status":"publish","type":"post","link":"https:\/\/www.omni-biotic.com\/sk-sk\/blog\/mozu-bakterie-pomahat-pri-hojeni-ran\/","title":{"rendered":"M\u00f4\u017eu bakt\u00e9rie pom\u00e1ha\u0165 pri hojen\u00ed r\u00e1n?"},"content":{"rendered":"\t\t
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Po\u010det bakt\u00e9ri\u00ed na na\u0161ej poko\u017eke je pomerne v\u00fdznamn\u00fd – pribli\u017ene 90 % v\u0161etk\u00fdch buniek tvoriacich na\u0161u poko\u017eku s\u00fa bakt\u00e9rie. Podobne ako v tr\u00e1viacom trakte, aj tu existuj\u00fa „priazniv\u00e9“ a „\u0161kodliv\u00e9“ druhy bakt\u00e9ri\u00ed.\u0160kodliv\u00e9 bakt\u00e9rie m\u00f4\u017eu predstavova\u0165 probl\u00e9m, predov\u0161etk\u00fdm v pr\u00edpade rozsiahlych alebo hlbok\u00fdch r\u00e1n, preto\u017ee m\u00f4\u017eu spomali\u0165 hojenie r\u00e1n.Na druhej strane, prvotn\u00e9 v\u00fdskumy nazna\u010duj\u00fa, \u017ee vhodn\u00e9 prospe\u0161n\u00e9 bakt\u00e9rie by mohli pon\u00faka\u0165 nov\u00fd terapeutick\u00fd pr\u00edstup k lie\u010dbe r\u00e1n: O tom, ak\u00fa rolu by v bud\u00facnosti mohli zohr\u00e1va\u0165 probiotik\u00e1 v oblasti hojenia r\u00e1n sme sa rozpr\u00e1vali s Univ. Prof. Dr. med. \u00a0Ewa Klara St\u00fcrmer.<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Hojenie r\u00e1n: \u010do zapr\u00ed\u010di\u0148uje, \u017ee sa rany nehoja?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Instutut AllergoSan: Ko\u013eko pacientov ro\u010dne m\u00e1 (v Nemecku) rany a ktor\u00e9 bakt\u00e9rie s\u00fa naj\u010dastej\u0161\u00edmi pr\u00ed\u010dinami nehojacich sa r\u00e1n?<\/em><\/p>

Je \u0165a\u017ek\u00e9 to odhadn\u00fa\u0165, preto\u017ee tak\u00edto zranen\u00ed<\/strong> pacienti<\/strong> sa lie\u010dia v r\u00f4znych odboroch. Ak ide o poopera\u010dn\u00e9 infekcie<\/strong>, potom ich samozrejme lie\u010dia predov\u0161etk\u00fdm pr\u00edslu\u0161n\u00ed chirurgovia a okrem toho aj cievni lek\u00e1ri, dermatol\u00f3govia, v\u0161eobecn\u00ed chirurgovia a diabetol\u00f3govia. Chronick\u00e9 rany<\/strong> teda nie s\u00fa priraden\u00e9 k \u017eiadnemu \u0161pecializovan\u00e9mu odboru. Z ve\u013ekej \u0161t\u00fadie PMV<\/strong> z roku 2016 v\u0161ak vieme, \u017ee v tom \u010dase tu bolo pribli\u017ene tri mili\u00f3ny pacientov s ranami<\/strong>. Asi dve tretiny z nich mali chronick\u00e9 rany<\/strong>. Pokia\u013e ide o „hlavn\u00fdch p\u00f4vodcov“ infekci\u00ed r\u00e1n<\/strong>, n\u00e1rodn\u00e9 aj medzin\u00e1rodn\u00e9 \u0161t\u00fadie identifikovali Staphylococcus<\/em> aureus<\/em> vo viac ako 50 %, z toho pribli\u017ene 9 % tvoril meticil\u00edn-rezistentn\u00fd Staphylococcus aureus<\/em> (MRSA). Treba v\u0161ak poveda\u0165, \u017ee pokia\u013e MRSA<\/strong> zost\u00e1va na rane, je rovnako citliv\u00fd na na\u0161e antiseptik\u00e1 ako „norm\u00e1lny“ Staphylococcus aureus<\/em>. Skuto\u010dn\u00fdm probl\u00e9mom sa st\u00e1va, ke\u010f sa povrchov\u00e1 infekcia rany vyvinie do hlbokej infekcie<\/strong> a roz\u0161\u00edri sa v tele. V\u00fdber antibiot\u00edk, ktor\u00e9 sa potom musia pou\u017ei\u0165, je kv\u00f4li rezistencii bakt\u00e9rie<\/strong> dos\u0165 obmedzen\u00fd<\/strong>. \u010eal\u0161ou bakt\u00e9riou, ktor\u00e1 \u010dasto kolonizuje chronick\u00e9 rany<\/strong>, je Pseudomonas aeruginosa<\/em> (30 %), \u010do plat\u00ed aj pre enterobakt\u00e9rie. V\u0161etky s\u00fa hlavn\u00fdmi nepriate\u013emi funk\u010dn\u00e9ho hojenia r\u00e1n<\/strong>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Cukrovka a hojenie r\u00e1n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Institut AllergoSan: S\u00fa pr\u00ed\u010dinou zle hojacich sa r\u00e1n ve\u013ek\u00e9 poranenia alebo m\u00f4\u017ee ma\u0165 tak\u00fdto probl\u00e9m aj mal\u00e9 \u0161krabnutie? A inak pre\u010do s\u00fa diabetici tak \u010dasto postihnut\u00ed poruchami hojenia r\u00e1n?
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Tieto rany nie s\u00fa<\/b> v\u00fdsledkom n\u00e1hodn\u00e9ho \u00farazu<\/b>. U star\u0161\u00edch pacientov trpiacich poruchami prekrvenia <\/b>n\u00f4h sa \u010dasto objavuj\u00fa v d\u00f4sledku zd\u00e1nlivo ban\u00e1lnych poranen\u00ed, ako s\u00fa mal\u00e9 ran<\/b>y po n\u00e1raze pri pr\u00e1ci v z\u00e1hrade, drobn\u00e9 \u0161krabance<\/b> na ruk\u00e1ch alebo dokonca odreniny <\/b>sp\u00f4soben\u00e9 hmyzom. Tieto zd\u00e1nliv\u00e9 nepodstatnosti sa v\u0161ak m\u00f4\u017eu zmeni\u0165 na chronick\u00e9 rany<\/b>. U diabetikov <\/b>je \u010dast\u00fdm probl\u00e9mom otvoren\u00e1 prele\u017eanina<\/b> na nohe. Vzh\u013eadom k tomu, \u017ee mnoh\u00ed diabetici trpia polyneuropatiou<\/b>, \u010do znamen\u00e1, \u017ee ich nervy u\u017e neposielaj\u00fa spr\u00e1vne sign\u00e1ly bolesti<\/b> napr\u00edklad pri tlaku na top\u00e1nku, \u010dasto doch\u00e1dza k vytvoreniu p\u013euzgierov, najm\u00e4 na chodidle alebo na kostn\u00fdch v\u00fdbe\u017ekoch. Tieto p\u013euzgiere <\/b>nesk\u00f4r praskn\u00fa a zmenia sa na chronick\u00e9 rany<\/b>.<\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Pokroky v o\u0161etrovan\u00ed a hojen\u00ed r\u00e1n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Institut AllergoSan: Ako laik m\u00e1 \u010dlovek niekedy pocit, \u017ee sa v starostlivosti o rany a poranenia neurobilo to\u013eko ako v in\u00fdch oblastiach medic\u00edny. Je to pravda, alebo ak\u00e1 je odborn\u00e1 realita?<\/i><\/span><\/p>

\u00c1no, v posledn\u00fdch rokoch, ke\u010f sa v\u0161etko s\u00fastredilo na COVID-19, sme v lie\u010dbe r\u00e1n<\/b> nezaznamenali \u017eiadne skuto\u010dn\u00e9 inov\u00e1cie<\/b>. Namiesto toho sme v\u0161ak zaznamenali podstatne viac a podstatne hor\u0161\u00edch „r\u00e1n“ v d\u00f4sledku strachu poranen\u00fdch pacientov<\/b> nav\u0161tevova\u0165 ambulancie a nemocnice a v d\u00f4sledku nedostatkov v starostlivosti v o\u0161etrovate\u013esk\u00fdch slu\u017eb\u00e1ch. Takzvan\u00e1 „modern\u00e1 lie\u010dba r\u00e1n“<\/b> existuje u\u017e 40 rokov. Zavedenie vlhkej terapie hojenia r\u00e1n <\/b>predstavovalo pokrok. Predt\u00fdm sa predpokladalo, \u017ee rany musia zaschn\u00fa\u0165<\/b>. V pr\u00edpade ak\u00fatnych r\u00e1n<\/b> to mo\u017eno st\u00e1le plat\u00ed, ale zavedenie <\/b>tejto novej filozofie vlhkej terapie bolo pr\u00ednosom pri chronick\u00fdch ran\u00e1ch<\/b>. Hoci v poslednom \u010dase nedo\u0161lo v tomto smere k \u017eiadnym skuto\u010dn\u00fdm inov\u00e1ci\u00e1m, materi\u00e1ly <\/b>na rany sa stali lep\u0161\u00edmi<\/b> a \u00fa\u010dinnej\u0161\u00edmi<\/b>. S\u00fa menej lepiv\u00e9 <\/b>a ten\u0161ie. Za zmienku stoj\u00ed aj rozvoj podtlakovej terapie<\/b>, pri ktorej sa rana prekryje \u0161pongiou a f\u00f3liou a udr\u017eiava sa vlhk\u00e1<\/b> a \u010dist\u00e1 <\/b>pod vplyvom podtlaku, \u010do stimuluje hojenie rany<\/b>. Okrem toho n\u00e1m priemysel zdravotn\u00edckych pom\u00f4cok v s\u00fa\u010dasnosti poskytol \u0161irok\u00fa \u0161k\u00e1lu \u00fa\u010dinn\u00fdch antimikrobi\u00e1lnych l\u00e1tok<\/b> a rie\u0161en\u00ed, <\/b>ktor\u00e9 n\u00e1m pom\u00e1haj\u00fa kontrolova\u0165 infekcie r\u00e1n<\/b> zvonka. Ale, \u017eia\u013e, nemysl\u00edm si, \u017ee by sme za posledn\u00fdch 15 rokov boli svedkami nejakej prevratnej vedy alebo pokrokov.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Antibiotik\u00e1 a porucha hojenia r\u00e1n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Institut AllergoSan: Antibiotik\u00e1 boli pre \u013eudstvo ve\u013ek\u00fdm pr\u00ednosom, ale \u010doraz v\u00e4\u010d\u0161\u00edm probl\u00e9mom sa st\u00e1va rast\u00faca odolnos\u0165 vo\u010di t\u00fdmto liekom. Je to probl\u00e9m aj v s\u00favislosti s o\u0161etrovan\u00edm r\u00e1n?<\/em><\/p>

Ka\u017ed\u00e1 chronick\u00e1 rana<\/b> obsahuje rozsiahlu popul\u00e1ciu bakt\u00e9ri\u00ed<\/b>. Ak tieto bakt\u00e9rie analyzujeme<\/b> pomocou PCR diagnostiky, m\u00f4\u017eeme identifikova\u0165 a\u017e 70 r\u00f4znych druhov<\/b>. Av\u0161ak nie je v\u017edy nutn\u00e9 rie\u0161i\u0165 tieto bakt\u00e9rie antibiotikami<\/b>. Ak v\u00fdsledok testu ukazuje pr\u00edtomnos\u0165 bakt\u00e9ri\u00ed, je d\u00f4le\u017eit\u00e9 zhodnoti\u0165 stav pacienta a rany<\/b>. Ka\u017ed\u00fd lek\u00e1r by mal najprv ur\u010di\u0165, \u010di ide len o koloniz\u00e1ciu rany, ktor\u00e1 pacientovi neprin\u00e1\u0161a zdravotn\u00e9 probl\u00e9my<\/b>, alebo \u010di ide o lok\u00e1lnu infekciu<\/b>, ba dokonca syst\u00e9mov\u00fa infekciu<\/b>. U pacientov s chronick\u00fdmi ranami<\/b> je v\u017edy riziko opakovan\u00fdch infekci\u00ed<\/b>. Predp\u00edsanie antibiot\u00edk by malo by\u0165 zva\u017eovan\u00e9 s rozvahou, preto\u017ee n\u00e1hodn\u00e9 predpisovanie antibiot\u00edk <\/b>by mohlo vies\u0165 k vzniku rezistentn\u00fdch bakt\u00e9ri\u00ed<\/b>. Typick\u00fd pacient s chronickou ranou<\/b> by mohol by\u0165 n\u00e1chyln\u00fd na infekcie<\/b> dva a\u017e trikr\u00e1t do roka, a nezv\u00e1\u017een\u00e9 pou\u017eitie antibiot\u00edk by mohlo prispie\u0165 k vzniku rezistentn\u00fdch bakt\u00e9ri\u00ed.<\/p>

Antibiotik\u00e1 <\/b>s\u00fa samozrejme pr\u00ednosom, ale u pacientov s chronick\u00fdmi ranami <\/b>by sa mali v\u017edy pou\u017e\u00edva\u0165 s opatrnos\u0165ou. Preto h\u013ead\u00e1me alternat\u00edvy, preto\u017ee napriek v\u0161etkej obozretnosti po\u010det rezistentn\u00fdch bakt\u00e9ri\u00ed narast\u00e1<\/b>.<\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Riziko infekcie r\u00e1n v nemocnici<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Ak\u00fa \u00falohu zohr\u00e1vaj\u00fa probiotik\u00e1 pri hojen\u00ed r\u00e1n?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Institut AllergoSan: Ak\u00e9 vysok\u00e9 je riziko infekcie rany v nemocnici? Existuj\u00fa ur\u010dit\u00e9 skupiny pacientov, ktor\u00e9 s\u00fa obzvl\u00e1\u0161\u0165 ohrozen\u00e9?<\/em><\/p>

Star\u0161\u00ed \u013eudia<\/b> – aj preto, \u017ee s prib\u00fadaj\u00facim vekom sa metabolick\u00e9 procesy spoma\u013euj\u00fa<\/b>. V skuto\u010dnosti s\u00fa to v\u0161ak \u010dastej\u0161ie pacienti s cukrovkou<\/span> <\/a>a obezitou<\/b>, ako aj pacienti, ktor\u00ed maj\u00fa oboje spolu, na z\u00e1klade tzv. metabolick\u00e9ho syndr\u00f3mu<\/b>. T\u00edto pacienti trpia komplexn\u00fdmi metabolick\u00fdmi poruchami, ktor\u00e9 tie\u017e s\u0165a\u017euj\u00fa hojenie r\u00e1n<\/b>. Okrem toho, samozrejme, mikrobi\u00f3m<\/span> <\/a>zohr\u00e1va v\u00fdznamn\u00fa \u00falohu<\/b> pri oneskorenom hojen\u00ed r\u00e1n<\/strong> u t\u00fdchto pacientov, preto\u017ee, ako je zn\u00e1me, maj\u00fa \u00faplne in\u00e9 zlo\u017eenie ko\u017en\u00e9ho a \u010drevn\u00e9ho mikrobi\u00f3mu<\/strong> a patog\u00e9nne z\u00e1rodky to maj\u00fa preto \u013eah\u0161ie.<\/p>

Institut AllergoSan: Cukrovka 2.\u00a0typu\u00a0(diabetes mellitus 2. typu) sa stal roz\u0161\u00edren\u00fdm ochoren\u00edm a diabetici \u010dasto z\u00e1pasia s probl\u00e9mami pri hojen\u00ed r\u00e1n. Ako dlho m\u00f4\u017ee trva\u0165, k\u00fdm sa diabetikovi zahoj\u00ed otvoren\u00e1 rana, a pre\u010do to tak je?<\/em><\/p>

Diabetick\u00e9 rany sa hoja<\/strong> ve\u013emi pomaly<\/strong>, rovnako ako rany u pacientov s poruchami art\u00e9riov\u00e9ho obehu<\/strong>. Toto spomalen\u00e9 hojenie r\u00e1n<\/strong> je spojen\u00e9 s hor\u0161ou imunitnou obranou a zn\u00ed\u017eenou mikrocirkul\u00e1ciou, ktor\u00e9 s\u00fa d\u00f4sledkom metabolick\u00e9ho syndr\u00f3mu. Vzh\u013eadom na z\u00e1kladn\u00e9 ochorenie je obrana proti infekci\u00e1m<\/strong> \u010dasto oslaben\u00e1<\/strong> a niekedy je potrebn\u00e9 telu pom\u00f4c\u0165 odstr\u00e1ni\u0165 patog\u00e9ny z r\u00e1n<\/strong> prostredn\u00edctvom pravideln\u00fdch v\u00fdmien tesn\u00fdch obv\u00e4zov. Toto v\u0161ak nie je v\u017edy dostato\u010dn\u00e9 a v praxi to nie je v\u017edy praktick\u00e9 pre pacientov a zdravotn\u00edckych pracovn\u00edkov.\u00a0<\/p>

Jednou z nov\u00fdch my\u0161lienok, ktor\u00e9 sa objavili, bolo zapojenie mikrobi\u00f3mu<\/strong> do procesu hojenia r\u00e1n<\/strong>. Jeho vplyv na zdravie \u010driev<\/span><\/strong><\/a> je dobre zn\u00e1my. A \u010drev\u00e1<\/strong>, sliznice<\/strong> a ko\u017ea<\/strong> <\/a><\/span>nemaj\u00fa a\u017e tak\u00fa odli\u0161n\u00fa \u0161trukt\u00faru; v\u0161etky s\u00fa kolonizovan\u00e9 bakt\u00e9riami<\/strong> a mechanizmy s\u00fa podobn\u00e9 na histologickej a bunkovej \u00farovni.<\/span>\u00a0T\u00fdmto sp\u00f4sobom sa m\u00f4\u017eu prepoji\u0165 poznatky z v\u00fdskumu \u010drevnej bari\u00e9ry<\/strong>, ktor\u00fd u\u017e ve\u013emi pokro\u010dil a vyu\u017ei\u0165 ich pri lie\u010dbe ko\u017en\u00fdch probl\u00e9mov<\/strong> a hojen\u00ed r\u00e1n<\/strong>.<\/span><\/p><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Institut AllergoSan: Ak\u00fa \u00falohu m\u00f4\u017eu probiotik\u00e1 zohr\u00e1va\u0165 pri hojen\u00ed r\u00e1n? Ak\u00fd je s\u00fa\u010dasn\u00fd stav vedeck\u00fdch poznatkov – mohli by probiotick\u00e9 bakt\u00e9rie hojenie r\u00e1n dokonca ur\u00fdchli\u0165?<\/em><\/p>

Pr\u00e1ve dokon\u010dujeme pilotn\u00fa \u0161t\u00fadiu <\/b>o vplyve \u0161pecifick\u00e9ho probiotika <\/span><\/a><\/b>na hojenie r\u00e1n <\/b>a s rados\u0165ou u\u017e m\u00f4\u017eem ozn\u00e1mi\u0165 novinku. Vybrali sme si viacdruhov\u00e9 probiotikum <\/b>\u0161peci\u00e1lne ur\u010den\u00e9 pre diabetikov<\/b> a metabolick\u00fd syndr\u00f3m<\/b>, ke\u010f\u017ee v\u0161etci na\u0161i pacienti v \u0161t\u00fadii<\/b> boli diabetici. Jedn\u00fdm z k\u013e\u00fa\u010dov\u00fdch zisten\u00ed bolo, \u017ee u\u017e\u00edvanie probiotika po\u010das \u0161iestich mesiacov<\/b> viedlo k pozit\u00edvnej zmene mikrobi\u00f3mu ko\u017ee<\/b> a rany<\/b> z patog\u00e9nneho na menej patog\u00e9nny. Je to p\u00f4sobiv\u00e9 vzh\u013eadom na to, \u017ee pacienti u\u017e\u00edvali probiotik\u00e1 <\/b>– peror\u00e1lne – r\u00e1no. Uk\u00e1zalo sa, \u017ee probiotick\u00e9 bakt\u00e9rie<\/b> <\/span><\/a>si na\u0161li cestu <\/b>cez \u00fastnu sliznicu a \u010drevo do ko\u017ee a nakoniec do rany<\/b>. V ka\u017edom pr\u00edpade je p\u00f4sobiv\u00e9, \u017ee peror\u00e1lny pr\u00edjem probiot\u00edk m\u00e1 pozit\u00edvny vplyv na ko\u017en\u00fd mikrobi\u00f3m<\/b>. D\u00fafam, \u017ee \u010doskoro na t\u00fato t\u00e9mu uskuto\u010dn\u00edme rozsiahlej\u0161iu \u0161t\u00fadiu a som si ve\u013emi ist\u00fd, \u017ee uveden\u00e9 \u00fa\u010dinky sa prejavia aj v tejto \u0161t\u00fadii. V pilotnej \u0161t\u00fadii sme tie\u017e videli, \u017ee\u00a0paradent\u00f3za\u00a0<\/b>sa v\u00fdrazne zlep\u0161ila u diabetikov<\/b>, a to takmer u v\u0161etk\u00fdch pacientov<\/b>. To bolo p\u00f4sobiv\u00e9! Ke\u010f si uvedom\u00edte, ako vyzer\u00e1 be\u017en\u00e1 parodontologick\u00e1 lie\u010dba – zd\u013ahav\u00e1, s mno\u017estvom n\u00e1v\u0161tev zub\u00e1ra, v\u00fdplachov \u00fast a bolestiv\u00fdch \u010disten\u00ed – u\u017e\u00edvanie probiot\u00edk po\u010das \u0161iestich mesiacov je jednoduch\u00fd sp\u00f4sob<\/b>, ako v\u00fdrazne zlep\u0161i\u0165 zdravie zubov<\/b>. In\u00fdmi slovami, probiotik\u00e1 maj\u00fa<\/b> rozhodne vplyv na poko\u017eku<\/span><\/a> a sliznice<\/b>. \u0164a\u017eko poveda\u0165, do akej miery bud\u00fa jedn\u00e9ho d\u0148a schopn\u00e9 nahradi\u0165 antibiotik\u00e1<\/strong><\/span><\/a>. Pri poh\u013eade do bud\u00facnosti si mysl\u00edm, \u017ee probiotik\u00e1 bud\u00fa \u010fal\u0161\u00edm n\u00e1strojom v terapii chronick\u00fdch r\u00e1n<\/strong>.<\/p>

Institut AllergoSan: Ako ste pri\u0161li na to, \u017ee probiotik\u00e1 m\u00f4\u017eu zohr\u00e1va\u0165 \u00falohu pri hojen\u00ed r\u00e1n?<\/em><\/p>

Moja v\u00fdskumn\u00e1 skupina uverejnila asi pred tromi rokmi \u0161t\u00fadiu, v ktorej sme v laborat\u00f3riu sk\u00famali \u00fa\u010dinok probiotick\u00fdch bakt\u00e9ri\u00ed na \u013eudsk\u00e9 patog\u00e9ny v bakteri\u00e1lnom biofilme. In\u00fdmi slovami, vytvorili sme biofilm z krvnej plazmy, imunitn\u00fdch buniek a bakt\u00e9ri\u00ed, ak\u00fd sa nach\u00e1dza na chronick\u00fdch ran\u00e1ch. Pomocou neho sme testovali, \u010di r\u00f4zne probiotik\u00e1 dok\u00e1\u017eu tento biofilm a bakt\u00e9rie v \u0148om zni\u010di\u0165. Na moje prekvapenie dok\u00e1zal Lactobacillus plantarum zabi\u0165 jeden z najagres\u00edvnej\u0161\u00edch ko\u017en\u00fdch z\u00e1rodkov, Pseudomonas aeruginosa, a potla\u010di\u0165 rast Staphylococcus aureus. Tieto pozorovania sa zatia\u013e uskuto\u010dnili len v experiment\u00e1lnom prostred\u00ed, ale v \u013eudskom prostred\u00ed, a teda u\u017e bl\u00edzko skuto\u010dn\u00e9mu \u013eudsk\u00e9mu biofilmu. Po\u010das v\u00fdskumov sme objavili ve\u013ek\u00fd potenci\u00e1l probiot\u00edk, aj ke\u010f v oblasti chronick\u00fdch r\u00e1n je e\u0161te ve\u013ea \u010do sk\u00fama\u0165, najm\u00e4 to, ktor\u00e9 „prospe\u0161n\u00e9“ mikroorganizmy potrebujeme: Ur\u010dite v\u0161ak m\u00f4\u017eeme ve\u013emi dobre vyu\u017ei\u0165 Lactobacillus plantarum.<\/p>

Hodnota pH v rane je v\u010faka nemu o nie\u010do kyslej\u0161ia, \u010do sa typick\u00fdm p\u00f4vodcom infekci\u00ed r\u00e1n v\u00f4bec nep\u00e1\u010di. Je to trochu ako D\u00e1vid a Goli\u00e1\u0161: preto\u017ee v probl\u00e9me infekci\u00ed r\u00e1n m\u00e1me do \u010dinenia s ve\u013emi agres\u00edvnymi z\u00e1rodkami, ktor\u00e9 s\u00fa teraz konfrontovan\u00e9 s mnoh\u00fdmi sympatick\u00fdmi mal\u00fdmi bakt\u00e9riami, ktor\u00e9 sa m\u00f4\u017eu premno\u017ei\u0165 a mo\u017eno aj zv\u00ed\u0165azi\u0165.<\/p><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\n Univ.-Prof. Dr. med. Ewa Klara St\u00fcrmer absolvovala \u0161t\u00fadium medic\u00edny na univerzit\u00e1ch v Essene a G\u00f6ttingene. Je odborn\u00ed\u010dkou v oblasti chirurgie, ortop\u00e9die a \u00farazovej chirurgie. V roku 1996 z\u00edskala doktor\u00e1t a v roku 2009 dosiahla kvalifik\u00e1ciu na v\u00fdskum a u\u010denie na Univerzite Georga Augusta v G\u00f6ttingene. V s\u00fa\u010dasnosti zast\u00e1va poz\u00edciu ved\u00facej chirurgick\u00e9ho oddelenia v Komplexnom centre pre rany a transla\u010dn\u00fd v\u00fdskum r\u00e1n na Univerzitnom medic\u00ednskom centre v Hamburgu-Eppendorfe (UKE). <\/div>\n <\/div>\n <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Po\u010det bakt\u00e9ri\u00ed na na\u0161ej poko\u017eke je pomerne v\u00fdznamn\u00fd – pribli\u017ene 90 % v\u0161etk\u00fdch buniek tvoriacich na\u0161u poko\u017eku s\u00fa bakt\u00e9rie. Podobne ako v tr\u00e1viacom trakte, aj tu existuj\u00fa „priazniv\u00e9“ a „\u0161kodliv\u00e9“ druhy bakt\u00e9ri\u00ed.\u0160kodliv\u00e9 bakt\u00e9rie m\u00f4\u017eu predstavova\u0165 probl\u00e9m, predov\u0161etk\u00fdm v pr\u00edpade rozsiahlych alebo hlbok\u00fdch r\u00e1n, preto\u017ee m\u00f4\u017eu spomali\u0165 hojenie r\u00e1n.Na druhej strane, prvotn\u00e9 v\u00fdskumy nazna\u010duj\u00fa, \u017ee vhodn\u00e9 […]<\/p>\n","protected":false},"author":17,"featured_media":21178,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[85,80],"tags":[],"class_list":["post-21164","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-novinky-vo-vyskume","category-staznosti-a-poradenstvo"],"acf":[],"rank_math":{"og:title":"M\u00f4\u017eu bakt\u00e9rie pom\u00e1ha\u0165 pri hojen\u00ed r\u00e1n? - OMNi-BiOTiC\u00ae","og:desc":"Hojenie r\u00e1n pri cukrovke prebieha ve\u013emi pomaly. D\u00e1 sa hojenie infek\u010dn\u00fdch a chronick\u00fdch r\u00e1n ur\u00fdchli\u0165? Nov\u00e9 pokroky pri hojen\u00ed a o\u0161etrovan\u00ed r\u00e1n.","og:url":"https:\/\/www.omni-biotic.com\/sk-sk\/blog\/mozu-bakterie-pomahat-pri-hojeni-ran\/","og:locale":"sk_SK","og:image":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-content\/uploads\/sites\/9\/2023\/10\/bakterie-hojenie-ran.jpg","og:image:width":"768","og:image:height":"384"},"additional_data":{"thumbnail":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-content\/uploads\/sites\/9\/2023\/10\/bakterie-hojenie-ran.jpg"},"blog_info":{"country":"sk-sk"},"_links":{"self":[{"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/posts\/21164","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/users\/17"}],"replies":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/comments?post=21164"}],"version-history":[{"count":7,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/posts\/21164\/revisions"}],"predecessor-version":[{"id":26396,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/posts\/21164\/revisions\/26396"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/media\/21178"}],"wp:attachment":[{"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/media?parent=21164"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/categories?post=21164"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/tags?post=21164"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}