{"id":23201,"date":"2025-04-11T10:30:51Z","date_gmt":"2025-04-11T08:30:51Z","guid":{"rendered":"https:\/\/www.omni-biotic.com\/sk-sk\/?p=23201"},"modified":"2025-04-11T10:54:36Z","modified_gmt":"2025-04-11T08:54:36Z","slug":"ako-znizit-cholesterol-bez-liekov","status":"publish","type":"post","link":"https:\/\/www.omni-biotic.com\/sk-sk\/blog\/ako-znizit-cholesterol-bez-liekov\/","title":{"rendered":"Zn\u00ed\u017ei\u0165 cholesterol bez liekov?"},"content":{"rendered":"\t\t
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Novinky vo v\u00fdskume<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Pod\u013ea \u0161t\u00fadie<\/strong> niektor\u00e9 \u010drevn\u00e9 bakt\u00e9rie<\/strong><\/a> rozkladaj\u00fa cholesterol<\/strong>, \u010do m\u00f4\u017ee ma\u0165 vplyv na zdravie<\/strong>: V anal\u00fdze americkej v\u00fdskumnej skupiny mali \u013eudia s vysokou koncentr\u00e1ciou <\/strong>t\u00fdchto bakt\u00e9ri\u00ed<\/strong> menej cholesterolu<\/strong> v \u010drev\u00e1ch a v krvi. Uviedol to t\u00edm pod veden\u00edm Ramnika Xaviera z Broad Institute v Cambridge vo vedeckom \u010dasopise „Cell“<\/strong>. Zmena bakteri\u00e1lnej diverzity<\/strong> \u010driev sa u\u017e dlho sp\u00e1ja s r\u00f4znymi ochoreniami vr\u00e1tane cukrovky<\/strong> <\/a>2. typu, obezity a z\u00e1palov\u00fdch ochoren\u00ed \u010driev<\/strong><\/a>. Xavierova skupina teraz zistila, \u017ee mikr\u00f3by v \u010drev\u00e1ch<\/strong> m\u00f4\u017eu prispieva\u0165 k zni\u017eovaniu<\/strong> hladiny cholesterolu<\/strong><\/a>, a t\u00fdm aj rizika kardiovaskul\u00e1rnych<\/strong> ochoren\u00ed u \u013eud\u00ed.<\/p>

Hoci hladinu cholesterolu ovplyv\u0148uj\u00fa g\u00e9ny<\/strong>, strava a \u017eivotn\u00fd \u0161t\u00fdl<\/strong>, in\u00fd t\u00edm pod veden\u00edm Xaviera u\u017e preuk\u00e1zal, \u017ee mikrobi\u00f3m<\/strong> <\/a>v \u010drev\u00e1ch m\u00f4\u017ee tie\u017e odb\u00farava\u0165 cholesterol<\/strong>, uv\u00e1dzaj\u00fa autori novej \u0161t\u00fadie. V \u0161t\u00fadii z roku 2020 v\u0161ak e\u0161te neboli podrobne analyzovan\u00e9 jednotliv\u00e9 bakteri\u00e1lne druhy<\/strong> a ich metabolizmus.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Niektor\u00e9 bakt\u00e9rie ovplyv\u0148uj\u00fa hladinu cholesterolu <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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T\u00edm teraz po prv\u00fdkr\u00e1t pou\u017eil \u00fadaje a vzorky stolice<\/strong> od 1 429 \u00fa\u010dastn\u00edkov Framingham Heart Study, ktor\u00e1 od roku 1948 systematicky analyzuje pr\u00ed\u010diny<\/strong> a rizik\u00e1<\/strong> kardiovaskul\u00e1rnych ochoren\u00ed u \u013eud\u00ed. Pomocou sekvenovania metagenomov<\/strong> t\u00edm dek\u00f3doval cel\u00fa DNA<\/strong> mikr\u00f3bov vo vzork\u00e1ch stolice. Pou\u017eil tie\u017e nov\u00fa technol\u00f3giu<\/strong> naz\u00fdvan\u00fa \u201eMetabolomics\u201c<\/strong> na zaznamenanie tis\u00edcov r\u00f4znych metabolick\u00fdch produktov.
V z\u00e1vere\u010dnej anal\u00fdze vedeck\u00fd t\u00edm objavil<\/strong> po\u010detn\u00e9 s\u00favislosti medzi r\u00f4znymi \u010drevn\u00fdmi bakt\u00e9riami<\/strong> a ur\u010dit\u00fdmi kardiovaskul\u00e1rnymi \u00fadajmi. Jedn\u00fdm z hlavn\u00fdch zisten\u00ed bolo, \u017ee \u013eudia s obzvl\u00e1\u0161\u0165 vysok\u00fdm po\u010dtom bakt\u00e9ri\u00ed<\/strong> z rodu Oscillibacter<\/em> v \u010drev\u00e1ch mali relat\u00edvne n\u00edzke hladiny cholesterolu<\/strong> v stolici a krvi. „V\u00fdsledky projektu zd\u00f4raz\u0148uj\u00fa v\u00fdznam vysokokvalitn\u00fdch, kur\u00e1torovan\u00fdch \u00fadajov o pacientoch,“ povedal jeden z dvoch hlavn\u00fdch autorov, Martin Stra\u017ear z Xavierovho laborat\u00f3ria. „To n\u00e1m umo\u017enilo v\u0161imn\u00fa\u0165 si \u00fa\u010dinky, ktor\u00e9 s\u00fa naozaj nepatrn\u00e9 a \u0165a\u017eko merate\u013en\u00e9, a priamo ich sledova\u0165.“<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n <\/i> <\/div>\n
\n V z\u00e1vere\u010dnej anal\u00fdze vedeck\u00fd t\u00edm objavil po\u010detn\u00e9 s\u00favislosti medzi r\u00f4znymi \u010drevn\u00fdmi bakt\u00e9riami a ur\u010dit\u00fdmi kardiovaskul\u00e1rnymi \u00fadajmi. <\/div>\n
\n <\/div>\n\n \n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Vedci vidia potenci\u00e1l pre nov\u00e9 terapeutick\u00e9 met\u00f3dy<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Ako v\u00fdskumn\u00e1 skupina zistila pomocou \u010fal\u0161\u00edch laborat\u00f3rnych experimentov<\/strong>, Oscillibacter<\/em> , bakt\u00e9ria<\/strong> zo skupiny klostr\u00eddi\u00ed (klaster IV), dok\u00e1\u017ee absorbova\u0165 cholesterol<\/strong> a premeni\u0165<\/strong> ho na koprostanol, ktor\u00fd je potom \u010falej rozkladan\u00fd <\/strong>in\u00fdmi bakt\u00e9riami<\/strong>. Rozhoduj\u00facim g\u00e9nom pre premenu cholesterolu<\/strong> je ismA. \u010eal\u0161ie \u0161t\u00fadie by mohli prispie\u0165 k v\u00fdvoju terapi\u00ed<\/strong>, ktor\u00e9 \u0161pecificky vyu\u017e\u00edvaj\u00fa funkciu \u010drevn\u00e9ho mikrobi\u00f3mu<\/strong>, p\u00ed\u0161u vedci. Napr\u00edklad opatrenia zameran\u00e9 na mikrobi\u00e1lny metabolizmus<\/a> cholesterolu<\/strong> v \u010drev\u00e1ch by mohli potenci\u00e1lne zn\u00ed\u017ei\u0165 vysok\u00fa hladinu cholesterolu<\/strong>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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ZDROJ:<\/strong> https:\/\/www.broadinstitute.org\/news\/scientists-link-certain-gut-bacteria-lower-heart-disease-risk<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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M\u00e1te ak\u00e9ko\u013evek ot\u00e1zky?<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Nap\u00ed\u0161te n\u00e1m! N\u00e1\u0161 vysokokvalifikovan\u00fd poradensk\u00fd t\u00edm zlo\u017een\u00fd z lek\u00e1rov, farmaceutov, biol\u00f3gov a odborn\u00edkov na v\u00fd\u017eivu je V\u00e1m k dispoz\u00edcii.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tKontakt<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Ako zn\u00ed\u017ei\u0165 cholesterol bez liekov? Nov\u00e1 \u0161t\u00fadia ukazuje: \u010crevn\u00e9 bakt\u00e9rie pom\u00e1haj\u00fa zni\u017eova\u0165 \u0161kodliv\u00fd cholesterol. Na hladinu cholesterolu v krvi maj\u00fa vplyv dedi\u010dn\u00e9 faktory a \u017eivotn\u00fd \u0161t\u00fdl. V\u00fdskumn\u00edci v USA teraz zistili, \u017ee d\u00f4le\u017eit\u00fa \u00falohu zohr\u00e1va aj mikrobi\u00f3m. Ich zistenia by mohli vies\u0165 k nov\u00fdm lie\u010debn\u00fdm postupom.<\/p>\n","protected":false},"author":17,"featured_media":9657,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[85],"tags":[],"class_list":["post-23201","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-novinky-vo-vyskume"],"acf":[],"rank_math":{"og:title":"Zn\u00ed\u017ei\u0165 cholesterol bez liekov? - OMNi-BiOTiC\u00ae","og:desc":"Ako zn\u00ed\u017ei\u0165 cholesterol bez liekov? Nov\u00e1 \u0161t\u00fadia ukazuje: \u010crevn\u00e9 bakt\u00e9rie pom\u00e1haj\u00fa zni\u017eova\u0165 \u0161kodliv\u00fd cholesterol. Vznikaj\u00fa nov\u00e9 lie\u010debn\u00e9 mo\u017enosti.","og:url":"https:\/\/www.omni-biotic.com\/sk-sk\/blog\/ako-znizit-cholesterol-bez-liekov\/","og:locale":"sk_SK","og:image":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-content\/uploads\/sites\/9\/2022\/08\/cholesterin-ausser-kontrolle-1.jpg","og:image:width":"1200","og:image:height":"718"},"additional_data":{"thumbnail":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-content\/uploads\/sites\/9\/2022\/08\/cholesterin-ausser-kontrolle-1.jpg"},"blog_info":{"country":"sk-sk"},"_links":{"self":[{"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/posts\/23201","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/users\/17"}],"replies":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/comments?post=23201"}],"version-history":[{"count":7,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/posts\/23201\/revisions"}],"predecessor-version":[{"id":26597,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/posts\/23201\/revisions\/26597"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/media\/9657"}],"wp:attachment":[{"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/media?parent=23201"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/categories?post=23201"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/tags?post=23201"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}