{"id":23629,"date":"2025-07-08T10:54:08Z","date_gmt":"2025-07-08T08:54:08Z","guid":{"rendered":"https:\/\/www.omni-biotic.com\/sk-sk\/?p=23629"},"modified":"2025-12-30T16:43:29Z","modified_gmt":"2025-12-30T15:43:29Z","slug":"suvislost-medzi-neplodnostou-a-vaginalnym-mikrobiomom","status":"publish","type":"post","link":"https:\/\/www.omni-biotic.com\/sk-sk\/blog\/suvislost-medzi-neplodnostou-a-vaginalnym-mikrobiomom\/","title":{"rendered":"S\u00favislos\u0165 medzi neplodnos\u0165ou a vagin\u00e1lnym mikrobi\u00f3mom"},"content":{"rendered":"\t\t
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V\u00fdsledky s\u00fa\u010dasnej \u0161t\u00fadie<\/strong> nazna\u010duj\u00fa, \u017ee zlo\u017eenie vagin\u00e1lnej mikrobioty<\/a><\/strong> by mohlo by\u0165 mo\u017enou pr\u00ed\u010dinou<\/strong> nevysvetlite\u013enej neplodnosti<\/strong>. Vedeck\u00e9 \u0161t\u00fadie uk\u00e1zali, \u017ee vagin\u00e1lny mikrobi\u00f3m<\/a> tehotn\u00fdch<\/strong> a netehotn\u00fdch \u017eien sa l\u00ed\u0161i<\/strong> z h\u013eadiska zlo\u017eenia a stability. To poskytuje n\u00e1znak, \u017ee vagin\u00e1lny mikrobi\u00f3m m\u00e1 vplyv na plodnos\u0165<\/strong> <\/a>a p\u00f4rod.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\u010co je zdrav\u00fd vagin\u00e1lny mikrobi\u00f3m?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Vagin\u00e1lny mikrobi\u00f3m<\/strong> tvor\u00ed pribli\u017ene 250 r\u00f4znych bakteri\u00e1lnych druhov<\/strong>. V zdravej vagin\u00e1lnej mikrobiote dominuj\u00fa laktobacily<\/strong><\/em>. Tieto bakt\u00e9rie mlie\u010dneho kvasenia<\/strong><\/a> zabezpe\u010duj\u00fa v po\u0161ve kysl\u00fa hodnotu pH<\/strong>, v ktorej sa patog\u00e9nne bakt\u00e9rie a plesne nem\u00f4\u017eu mno\u017ei\u0165. P\u00f4sob\u00ed preto ako d\u00f4le\u017eit\u00fd ochrann\u00fd \u0161t\u00edt proti infekci\u00e1m<\/strong> v int\u00edmnej oblasti, ako s\u00fa infekcie mo\u010dov\u00fdch ciest<\/strong><\/a>, vagin\u00e1lne kvasinkov\u00e9 infekcie<\/strong> alebo bakteri\u00e1lna vagin\u00f3za<\/strong><\/a>.<\/p>

Bakteri\u00e1lna rovnov\u00e1ha<\/strong> vagin\u00e1lneho mikrob\u00f3mu sa v\u0161ak m\u00f4\u017ee sta\u0165 nestabilnou<\/strong>. Existuje na to mnoho d\u00f4vodov: hormon\u00e1lne zmeny<\/strong>, hormon\u00e1lna nerovnov\u00e1ha<\/strong><\/a>, \u00a0oslaben\u00fd imunitn\u00fd syst\u00e9m<\/strong> <\/a>alebo antibiotik\u00e1<\/strong> <\/a>m\u00f4\u017eu v\u00e1\u017ene naru\u0161i\u0165 rovnov\u00e1hu vo vag\u00edne<\/strong>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Ak\u00e1 je s\u00favislos\u0165 medzi plodnos\u0165ou a mikrobi\u00f3mom?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Vagin\u00e1lna dysbi\u00f3za<\/strong>, t. j. nerovnov\u00e1ha vagin\u00e1lnej mikrobioty<\/strong><\/a> sp\u00f4soben\u00e1 zn\u00ed\u017een\u00fdm v\u00fdskytom laktobacilov<\/em> a s t\u00fdm spojen\u00fdm premno\u017een\u00edm anaer\u00f3bnych bakt\u00e9ri\u00ed, m\u00f4\u017ee ma\u0165 okrem in\u00e9ho negat\u00edvny vplyv na reproduk\u010dn\u00fa schopnos\u0165<\/strong>. Napr\u00edklad koloniz\u00e1cia po\u0161vy z\u00e1rodkom Ureaplasma parvum<\/strong><\/em> sa sp\u00e1ja s neplodnos\u0165ou<\/strong> a perinat\u00e1lnymi ochoreniami.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\u010casto podce\u0148ovan\u00e9: \u00faloha maternicovej sliznice<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Ani sliznica maternice<\/strong> nie je steriln\u00e1, ale je os\u00eddlen\u00e1 bakt\u00e9riami, ktor\u00e9 maj\u00fa v\u00fdznamn\u00fd vplyv na plodnos\u0165<\/strong> \u017eeny. Naru\u0161en\u00e1<\/strong> bakteri\u00e1lna<\/strong> koloniz\u00e1cia<\/strong> m\u00f4\u017ee br\u00e1ni\u0165 uhniezdeniu oplodnen\u00e9ho vaj\u00ed\u010dka<\/strong>.<\/p>

Jedna \u0161t\u00fadia<\/strong> <\/a>uk\u00e1zala, \u017ee mikrobi\u00f3m<\/strong> v\u00e4\u010d\u0161iny zdrav\u00fdch \u017eien pozost\u00e1val z viac ako 90 % z laktobacilov<\/em><\/strong>. Pri mikrobi\u00f3me s prevahou laktobacilov<\/em> v maternici sa po\u010das prv\u00e9ho umel\u00e9ho oplodnenia \u00faspe\u0161ne implantovalo 60,7 % embry\u00ed<\/strong> v porovnan\u00ed s iba 23,1 % pri mikrobi\u00f3me so zn\u00ed\u017een\u00fdm obsahom laktobacilov<\/em>.<\/p>

Podiel \u00faspe\u0161n\u00fdch tehotenstiev<\/strong> <\/a>sa pri nedostatku<\/strong> laktobacilov<\/em> zn\u00ed\u017eil zo 70,6 % na 33,3 %<\/strong> a podiel \u017eivonaroden\u00fdch det\u00ed klesol z 58,8 % na 6,7 %.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Probiotik\u00e1 pri opakuj\u00facich sa infekci\u00e1ch<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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V posledn\u00fdch rokoch rastie v\u00fdznam<\/strong> pou\u017e\u00edvania probiot\u00edk<\/strong><\/a> ako terapeutick\u00e9ho<\/strong> alebo prevent\u00edvneho<\/strong> opatrenia pri negat\u00edvnych zmen\u00e1ch vagin\u00e1lneho mikrobi\u00f3mu<\/strong> a opakuj\u00facich sa infekci\u00e1ch<\/strong> mo\u010dov\u00e9ho a vagin\u00e1lneho<\/strong> traktu.<\/p>

V\u010faka v\u00fdskumu mikrobi\u00f3mu<\/a><\/strong> sa tie\u017e preuk\u00e1zalo, \u017ee indika\u010dne \u0161pecifick\u00e9 viacdruhov\u00e9 probiotik\u00e1<\/strong><\/a> by sa mali v ide\u00e1lnom pr\u00edpade u\u017e\u00edva\u0165<\/strong> peror\u00e1lne<\/strong>. Ide o prirodzen\u00fd sp\u00f4sob koloniz\u00e1cie po\u0161vy. \u017delan\u00e9 laktobacily<\/em> migruj\u00fa z \u010dreva do po\u0161vy<\/strong> hlienovou cestou. Na rozdiel od vagin\u00e1lnych kaps\u00fal sa pri peror\u00e1lnom u\u017e\u00edvan\u00ed vytv\u00e1ra v \u010dreve z\u00e1sob\u00e1re\u0148<\/strong>, z ktorej m\u00f4\u017eu bakt\u00e9rie mlie\u010dneho kvasenia<\/strong> trvalo migrova\u0165 do po\u0161vy<\/strong>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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M\u00f4\u017ee sa plodnos\u0165 podpori\u0165 u\u017e\u00edvan\u00edm viacdruhov\u00fdch probiot\u00edk?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Jedna \u0161t\u00fadia uk\u00e1zala<\/strong>, \u017ee u\u017e\u00edvanie viacdruhov\u00e9ho probiotika<\/strong><\/a> m\u00f4\u017ee ma\u0165 vplyv na vagin\u00e1lnu koloniz\u00e1ciu<\/strong> Ureaplasma parvum<\/em>. Zatia\u013e \u010do v skupine, ktor\u00e1 dost\u00e1vala placebo<\/strong>, do\u0161lo k zv\u00fd\u0161eniu<\/strong> v\u00fdskytu<\/strong> tohto patog\u00e9nu<\/strong><\/a>, v skupine, ktor\u00e1 dost\u00e1vala viaczlo\u017ekov\u00e9 probiotikum<\/strong><\/a>, sa tento n\u00e1rast takmer neprejavil<\/strong>. Pou\u017e\u00edvanie viaczlo\u017ekov\u00e9ho probiotika preto pon\u00faka optim\u00e1lnu mo\u017enos\u0165 udr\u017eania zdrav\u00e9ho vagin\u00e1lneho mikrobi\u00f3mu<\/strong> a predstavuje aj mo\u017enos\u0165 podpornej lie\u010dby<\/strong> \u017eien<\/strong> s nenaplnenou t\u00fa\u017ebou ma\u0165 deti.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Neplodnos\u0165 je celosvetovo roz\u0161\u00edren\u00fd probl\u00e9m, v ktorom popri veku, genetick\u00fdch predispoz\u00edci\u00e1ch a \u017eivotnom \u0161t\u00fdle zohr\u00e1vaj\u00fa hlavn\u00fa \u00falohu ak\u00fatne a chronick\u00e9 infekcie. V posledn\u00fdch rokoch sa v\u00fdskum zameral na vagin\u00e1lnu mikrobiotu pri lie\u010dbe neplodnosti.<\/p>\n","protected":false},"author":17,"featured_media":23632,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[87,85,81],"tags":[],"class_list":["post-23629","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-matka-a-dieta","category-novinky-vo-vyskume","category-zdravie-zeny"],"acf":[],"rank_math":{"og:title":"S\u00favislos\u0165 medzi neplodnos\u0165ou a vagin\u00e1lnym mikrobi\u00f3mom","og:desc":"Pod\u013ea vedeck\u00fdch \u0161t\u00fadi\u00ed m\u00f4\u017ee naru\u0161en\u00e1 bakteri\u00e1lna koloniz\u00e1cia br\u00e1ni\u0165 uhniezdeniu oplodnen\u00e9ho vaj\u00ed\u010dka. Optim\u00e1lnou podporou m\u00f4\u017eu by\u0165 probiotik\u00e1.","og:url":"https:\/\/www.omni-biotic.com\/sk-sk\/blog\/suvislost-medzi-neplodnostou-a-vaginalnym-mikrobiomom\/","og:locale":"sk_SK","og:image":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-content\/uploads\/sites\/9\/2024\/05\/neplodnost-plodnost-vaginalny-mikrobiom.jpg","og:image:width":"700","og:image:height":"500"},"additional_data":{"thumbnail":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-content\/uploads\/sites\/9\/2024\/05\/neplodnost-plodnost-vaginalny-mikrobiom.jpg"},"blog_info":{"country":"sk-sk"},"_links":{"self":[{"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/posts\/23629","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/users\/17"}],"replies":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/comments?post=23629"}],"version-history":[{"count":7,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/posts\/23629\/revisions"}],"predecessor-version":[{"id":28297,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/posts\/23629\/revisions\/28297"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/media\/23632"}],"wp:attachment":[{"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/media?parent=23629"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/categories?post=23629"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.omni-biotic.com\/sk-sk\/wp-json\/wp\/v2\/tags?post=23629"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}